Cisplatin

checkpoint kinase 1 ; Homo sapiens







65 Article(s)
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51 20623183 Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G₂/M checkpoint signaling. 2011 Jun 1
52 21592546 The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog. 2011 Aug 1
53 22037398 Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation. 2011 Nov 1 1
54 19931410 Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells. 2010 Feb 2
55 20619533 Chk1 inhibitor Gö6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo. 2010 Nov 28 1
56 20700484 NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway. 2010 Aug 5 2
57 20722101 RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells. 2010 Sep 3
58 19713747 Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymerase eta-deficient human cells. 2009 Sep 15 1
59 20137342 [Silencing of cell cycle checkpoint kinase gene enhances cisplatin-induced apoptosis of lung cancer cells]. 2009 Nov 1
60 17268080 Checkpoint kinase 1 is cleaved in a caspase-dependent pathway during genotoxic stress-induced apoptosis. 2007 Feb 1
61 18159231 Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. 2007 Dec 26 1
62 16424027 Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation. 2006 Jan 15 2
63 16849332 The involvement of ataxia-telangiectasia mutated protein activation in nucleotide excision repair-facilitated cell survival with cisplatin treatment. 2006 Sep 15 1
64 12740909 Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells. 2003 Jul 10 1
65 11152453 DNA Damage Induces p53-dependent Down-regulation of hCHK1. 2001 Apr 6 3