Tyrosine

signal transducer and activator of transcription 5A ; Mus musculus







116 Article(s)
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1 35192696 A novel intramolecular negative regulation of mouse Jak3 activity by tyrosine 820. 2022 Jun 4 1
2 31924648 IL-7R-Dependent Phosphatidylinositol 3-Kinase Competes with the STAT5 Signal to Modulate T Cell Development and Homeostasis. 2020 Feb 15 1
3 24983364 Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. 2014 Aug 26 1
4 23631823 Effects of insulin and IGF-I on growth hormone- induced STAT5 activation in 3T3-F442A adipocytes. 2013 Apr 30 1
5 22130676 Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. 2012 Jan 13 3
6 23264850 The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations. 2012 Jul 2
7 24058773 Acetylation and sumoylation control STAT5 activation antagonistically. 2012 Jul 1 5
8 21397011 Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription. 2011 Jul 1
9 20028972 STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant. 2010 Feb 19 2
10 20858858 Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease. 2010 Dec 23 1
11 20980634 Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. 2010 Dec 1 1
12 21036145 Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells. 2010 Nov 26 2
13 19185518 A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells. 2009 Feb 20 1
14 19788420 A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A. 2009 Nov 1
15 17980909 Expression of the GPI-anchored receptor Prv-1 enhances thrombopoietin and IL-3-induced proliferation in hematopoietic cell lines. 2008 May 1
16 18335503 TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism. 2008 Aug 1 1
17 18368071 RNAi-mediated silencing of p190Bcr-Abl inactivates Stat5 and cooperates with imatinib mesylate and 17-allylamino-17-demetoxygeldanamycin in selective killing of p190Bcr-Abl-expressing leukemia cells. 2008 Jun 1
18 18566415 MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling. 2008 Jul 1 5
19 18653779 Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation. 2008 Oct 1
20 19011510 STAT5 contributes to antiapoptosis in melanoma. 2008 Dec 1
21 17234744 Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells. 2007 May 1 1
22 17372307 The modulation of STAT5A/GR complexes during fat cell differentiation and in mature adipocytes. 2007 Mar 3
23 17726024 The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms. 2007 Oct 19 2
24 15982852 Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression. 2006 Feb 1
25 16532027 Constitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis. 2006 Aug 3 4
26 16627759 Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD. 2006 Aug 15 3
27 15671076 Renal cells express a functional interleukin-15 receptor. 2005 Mar 1
28 15988755 Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells. 2005 Oct 1 1
29 16216905 Regulation of pancreatic beta-cell mass and proliferation by SOCS-3. 2005 Oct 1
30 16337084 The compartmentalization of prolactin signaling in the mouse mammary gland. 2005 Dec 21 1
31 16423818 Increased sensitivity to GH in liver of Ames dwarf (Prop1df/Prop1df) mice related to diminished CIS abundance. 2005 Dec 2
32 15240680 Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases. 2004 Jul 15 4
33 15334659 Dominant negative Ras enhances lactogenic hormone-induced differentiation by blocking activation of the Raf-Mek-Erk signal transduction pathway. 2004 Nov 2
34 15500144 [Role of interleukin-5 in immune regulation and inflammation]. 2004 Oct 1
35 12596040 Suppression of beta-casein gene expression by inhibition of protein synthesis in mouse mammary epithelial cells is associated with stimulation of NF-kappaB activity and blockage of prolactin-Stat5 signaling. 2003 Feb 1
36 12611881 Activating transcription factor 4 overexpression inhibits proliferation and differentiation of mammary epithelium resulting in impaired lactation and accelerated involution. 2003 May 9 1
37 12637316 IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells. 2003 Jul 1 2
38 12748279 Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling. 2003 Jun 1
39 12809512 Different biological effects of unmodified prolactin and a molecular mimic of phosphorylated prolactin involve different signaling pathways. 2003 Jun 24 2
40 12901872 Role of Stat5 in type I interferon-signaling and transcriptional regulation. 2003 Aug 22 1
41 14662339 Hematopoietic cell survival signals are elicited through non-tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway. 2003 Dec 3
42 11909529 The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. 2002 Mar 19 1
43 11981045 Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium. 2002 May 2
44 12193575 c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription. 2002 Sep 1
45 12220225 Role of the protein tyrosine phosphatase SHP-1 (Src homology phosphatase-1) in the regulation of interleukin-3-induced survival, proliferation and signalling. 2002 Dec 15 1
46 12231477 Induction of interleukin-2 receptor alpha (IL-2Ralpha) expression by interleukin-2: important role of the interleukin-2 receptor beta chain region between the two Stat5 docking sites. 2002 Jul-Sep 1
47 12349947 Tyrosine phosphorylation-mediated signal transduction in MCP-1-induced macrophage activation: role for receptor dimerization, focal adhesion protein complex and JAK/STAT pathway. 2002 Jul 1
48 12388746 Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. 2002 Oct 1
49 12429573 Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid. 2002 Dec 1
50 11205741 Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells. 2001 Jan 1