Ascorbic Acid

solute carrier family 23 member 2 ; Homo sapiens







112 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32008465 Vitamin C supplementation had no side effect in non-cancer, but had anticancer properties in ovarian cancer cells. 2021 Jun 1
2 33307167 Activation of adenosine A3 receptors regulates vitamin C transport and redox balance in neurons. 2021 Feb 1 3
3 33484802 New insights into Vitamin C function: Vitamin C induces JAK2 activation through its receptor-like transporter SVCT2. 2021 Mar 15 4
4 33580460 Role of p53 in transcriptional repression of SVCT2. 2021 Feb 7
5 33677235 Ascorbic acid analogue 6-Deoxy-6-[18F] fluoro-L-ascorbic acid as a tracer for identifying human colorectal cancer with SVCT2 overexpression. 2021 May 1
6 34285658 Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake. 2021 4
7 34403723 Histone deacetylase inhibitors regulate vitamin C transporter functional expression in intestinal epithelial cells. 2021 Dec 2
8 34405001 Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer. 2021 2
9 34439814 Vitamin C Enhances Antiviral Functions of Lung Epithelial Cells. 2021 Aug 3 4
10 34573045 SVCT2 Overexpression and Ascorbic Acid Uptake Increase Cortical Neuron Differentiation, Which Is Dependent on Vitamin C Recycling between Neurons and Astrocytes. 2021 Sep 3 3
11 34599650 Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples. 2021 Oct 2 1
12 34673103 Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake. 2021 Dec 1 3
13 34703915 Alterations on vitamin C synthesis and transportation and egg deposition induced by dietary vitamin C supplementation in Hy-Line Brown layer model. 2021 Dec 2
14 31901552 Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation. 2020 Feb 1
15 32080778 Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells. 2020 Apr 1
16 32580031 SVCT2-Dependent plasma and mitochondrial membrane transport of ascorbic acid in differentiating myoblasts. 2020 Sep 2
17 32751086 Vitamin C Deficiency and the Risk of Osteoporosis in Patients with an Inflammatory Bowel Disease. 2020 Jul 29 1
18 30285481 Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway. 2019 Jan 1 1
19 30565018 Vitamin C Attenuates Sodium Fluoride-Induced Mitochondrial Oxidative Stress and Apoptosis via Sirt1-SOD2 Pathway in F9 Cells. 2019 Sep 1
20 30616065 MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells. 2019 Mar 1
21 30660746 Ascorbic acid-modified brain-specific liposomes drug delivery system with "lock-in" function. 2019 Nov 1
22 30902760 Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer. 2019 May 1 1
23 31002656 Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). 2019 Apr 19 1
24 31143097 Dopamine-Induced Ascorbate Release From Retinal Neurons Involves Glutamate Release, Activation of AMPA/Kainate Receptors and Downstream Signaling Pathways. 2019 5
25 31214276 Intramelanocytic Acidification Plays a Role in the Antimelanogenic and Antioxidative Properties of Vitamin C and Its Derivatives. 2019 4
26 31594969 Basal Sodium-Dependent Vitamin C Transporter 2 polarization in choroid plexus explant cells in normal or scorbutic conditions. 2019 Oct 8 2
27 29030247 Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. 2018 Feb 1
28 29476450 Dopamine Promotes Ascorbate Release from Retinal Neurons: Role of D1 Receptors and the Exchange Protein Directly Activated by cAMP type 2 (EPAC2). 2018 Oct 1
29 29545069 Ascorbic acid increases SVCT2 localization at the plasma membrane by accelerating its trafficking from early secretory compartments and through the endocytic-recycling pathway. 2018 May 20 1
30 29872720 Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2. 2018 1
31 30054560 Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. 2018 Jul 27 10
32 26838684 Fruit and vegetable intake and vitamin C transporter gene (SLC23A2) polymorphisms in chronic lymphocytic leukaemia. 2017 Apr 1
33 27596508 Apical Polarization of SVCT2 in Apical Radial Glial Cells and Progenitors During Brain Development. 2017 Sep 3
34 27932501 Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. 2017 Apr 1 2
35 28351945 Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype. 2017 Mar 28 4
36 28385602 SVCT-2 determines the sensitivity to ascorbate-induced cell death in cholangiocarcinoma cell lines and patient derived xenografts. 2017 Jul 10 1
37 27012422 L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells. 2016 Jun 7
38 27382510 Vitamin C is taken up by human T cells via sodium-dependent vitamin C transporter 2 (SVCT2) and exerts inhibitory effects on the activation of these cells in vitro. 2016 Jun 2
39 27476024 Corrigendum to 'L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells': [Free Radic. Biol. Med. 95 (2016) 200-208]. 2016 Aug 1
40 25014399 Functional characterization and molecular identification of vitamin C transporter (SVCT2) in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells. 2015 May 2
41 25451960 In silico aided thoughts on mitochondrial vitamin C transport. 2015 Jan 21 1
42 25645015 Ascorbic acid transport in brain microvascular pericytes. 2015 Mar 6 3
43 25854967 Identification of vitamin C transporters in the human airways: a cross-sectional in vivo study. 2015 Apr 8 3
44 26188149 Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria. 2015 Sep 1
45 26210298 The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis. 2015 Sep 4
46 26340060 Ascorbic acid efflux from human brain microvascular pericytes: role of re-uptake. 2015 Sep-Oct 9
47 26403401 CAPACITIVE COUPLING ELECTRIC FIELDS IN THE TREATMENT OF VERTEBRAL COMPRESSION FRACTURES. 2015 Jul-Sep 1
48 26779027 Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain. 2015 1
49 24365600 Knockdown of SVCT2 impairs in-vitro cell attachment, migration and wound healing in bone marrow stromal cells. 2014 Mar 1
50 24594434 Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2. 2014 May 2