Pub. Date : 2021 Mar 15
PMID : 33484802
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | New insights into Vitamin C function: Vitamin C induces JAK2 activation through its receptor-like transporter SVCT2. | Ascorbic Acid | solute carrier family 23 member 2 | Homo sapiens |
| 2 | New insights into Vitamin C function: Vitamin C induces JAK2 activation through its receptor-like transporter SVCT2. | Ascorbic Acid | solute carrier family 23 member 2 | Homo sapiens |
| 3 | Here, we propose that VitC is also a bio-signaling molecule based on the finding that sodium-dependent VitC transporter (SVCT) 2 is a novel receptor-like transporter of VitC that possesses dual activities in mediating VitC uptake and Janus kinase (JAK) 2/signal transducer and activator of transcription (STAT) 2 signaling pathway. | Ascorbic Acid | solute carrier family 23 member 2 | Homo sapiens |
| 4 | Through interaction, SVCT2 induces JAK2 phosphorylation while transporting VitC into cells. | Ascorbic Acid | solute carrier family 23 member 2 | Homo sapiens |