| 1 |
35226304 | Assessment of the Effects of Inhibition or Induction of CYP2C19 and CYP2C9 Enzymes, or Inhibition of OAT3, on the Pharmacokinetics of Abrocitinib and Its Metabolites in Healthy Individuals. | 2022 May |
1 |
| 2 |
35490380 | Blockade of Organic Anion Transport in Humans After Treatment With the Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine. | 2022 May 1 |
2 |
| 3 |
33307708 | Probenecid Increases the Concentration of 7-Chlorokynurenic Acid Derived from the Prodrug 4-Chlorokynurenine within the Prefrontal Cortex. | 2021 Jan 4 |
1 |
| 4 |
33609918 | Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. | 2021 Mar-Apr |
1 |
| 5 |
33632715 | Clinical Investigation of Metabolic and Renal Clearance Pathways Contributing to the Elimination of Fevipiprant Using Probenecid as Perpetrator. | 2021 May |
1 |
| 6 |
34599018 | Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition. | 2021 Dec |
1 |
| 7 |
31760750 | Interaction of Organic Anion Transporter 3-Mediated Uptake of Steviol Acyl Glucuronide, a Major Metabolite of Rebaudioside A, with Selected Drugs. | 2020 Feb 12 |
1 |
| 8 |
32373203 | Organic anion transporters also mediate the drug-drug interaction between imipenem and cilastatin. | 2020 Mar |
1 |
| 9 |
32723847 | Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans. | 2020 Oct |
2 |
| 10 |
27278858 | Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. | 2017 Apr |
1 |
| 11 |
28559139 | Effects of phenylpropanoids on human organic anion transporters hOAT1 and hOAT3. | 2017 Aug 5 |
1 |
| 12 |
28749581 | Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib. | 2017 Nov |
1 |
| 13 |
27163499 | Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. | 2016 May |
1 |
| 14 |
27638508 | Investigation of Endogenous Compounds Applicable to Drug-Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans. | 2016 Dec |
1 |
| 15 |
25653502 | Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide. | 2015 |
2 |
| 16 |
26133709 | Time-Dependent Inhibition of hOAT1 and hOAT3 by Anthraquinones. | 2015 |
1 |
| 17 |
24185403 | Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate, a uremic toxin. | 2014 Oct |
1 |
| 18 |
24616266 | Assessment of the mass balance recovery and metabolite profile of avibactam in humans and in vitro drug-drug interaction potential. | 2014 May |
2 |
| 19 |
24685584 | Interaction of five anthraquinones from rhubarb with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8) and drug-drug interaction in rats. | 2014 May 14 |
2 |
| 20 |
23297298 | Brain efflux index to investigate the influence of active efflux on brain distribution of pemetrexed and methotrexate. | 2013 Mar |
2 |
| 21 |
23457060 | Chlorothiazide is a substrate for the human uptake transporters OAT1 and OAT3. | 2013 May |
2 |
| 22 |
22108572 | Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3. | 2012 Feb |
1 |
| 23 |
20360303 | Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters. | 2010 Jul |
1 |
| 24 |
20508390 | Interactions of human organic anion transporters with aristolochic acids. | 2010 |
1 |
| 25 |
20519552 | Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1). | 2010 Sep 1 |
1 |
| 26 |
19074525 | The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine. | 2009 Mar |
1 |
| 27 |
19378467 | Assessment of the renal toxicity of novel anti-inflammatory compounds using cynomolgus monkey and human kidney cells. | 2009 Apr 5 |
2 |
| 28 |
19394312 | Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural. | 2009 Aug 15 |
1 |
| 29 |
17314201 | Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein. | 2007 May |
2 |
| 30 |
17329910 | Characterization of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, and meropenem as substrates of human renal transporters. | 2007 Feb 25 |
1 |
| 31 |
17578901 | Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices. | 2007 Sep |
1 |
| 32 |
16455804 | Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. | 2006 May |
3 |
| 33 |
15948029 | Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices. | 2005 Jun |
1 |
| 34 |
16006492 | A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters. | 2005 Oct |
2 |
| 35 |
15377641 | Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters. | 2004 Oct |
2 |
| 36 |
12650826 | Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. | 2003 Mar 28 |
1 |
| 37 |
12130730 | Characterization of methotrexate transport and its drug interactions with human organic anion transporters. | 2002 Aug |
4 |
| 38 |
11426832 | Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. | 2001 May 11 |
2 |