Title : Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition.

Pub. Date : 2021 Dec

PMID : 34599018






1 Functional Relationships(s)
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1 Significance Statement We reported that probenecid, an OAT1 and OAT3 inhibitor, significantly increased the plasma concentrations of kynurenic acid and several uremic acids in human subjects. Probenecid solute carrier family 22 member 8 Homo sapiens