Title : Characterization of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, and meropenem as substrates of human renal transporters.

Pub. Date : 2007 Feb 25

PMID : 17329910






1 Functional Relationships(s)
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1 The Km value of the hOAT3-mediated transport was 847 microM, and the uptake was inhibited by probenecid, p-aminohippurate and benzylpenicillin with Ki values of 3.76, 712, and 202 microM, respectively. Probenecid solute carrier family 22 member 8 Homo sapiens