Tadalafil

phosphodiesterase 5A ; Homo sapiens







301 Article(s)
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1 34872842 Retrospective Observational Real-World Outcome Study to Evaluate Safety Among Patients With Erectile Dysfunction (ED) With Co-Possession of Tadalafil and Anti-Hypertensive Medications (anti-HTN). 2022 Jan 2
2 35119252 Effects of Tadalafil on skeletal muscle tissue: exploring interactions and novel mechanisms of action. 2022 Feb 4 4
3 35135037 The PASTIS trial: Testing tadalafil for possible use in vascular cognitive impairment. 2022 Feb 8 1
4 35457011 Tadalafil and Steroid Hormones Interactions in Adipose, Bone and Prostate Tissues: Focus on Translational Perspectives. 2022 Apr 11 2
5 35530128 Free energy perturbation (FEP)-guided scaffold hopping. 2022 Mar 1
6 33718200 New Approaches in Oncology for Repositioning Drugs: The Case of PDE5 Inhibitor Sildenafil. 2021 1
7 34006491 Digital Real-world Data Suggest Patient Preference for Tadalafil over Sildenafil in Patients with Erectile Dysfunction. 2021 May 15 2
8 34182826 Tadalafil Reverses the Effect of Three-Dimensional Cell Culture System on Stem Cell Features in A549 and SK-MES-1. 2021 Jul 2
9 34440764 Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. 2021 Aug 5 1
10 34471575 Is Tadalafil an Effective Treatment Option for Interstitial Cystitis/Painful Bladder Syndrome? A Report of a Challenging Case. 2021 Jul 1
11 34471776 On the Viability of Tadalafil-Based 18F-Radiotracers for In Vivo Phosphodiesterase 5 (PDE5) PET Imaging. 2021 Aug 24 4
12 34926008 Bilateral Sequential Non-arteritic Anterior Ischemic Optic Neuropathy (NAION). 2021 Nov 2
13 31654676 The role of PDE5a in oocyte maturation of zebrafish. 2020 Jan 15 1
14 32378365 Should All Men with Type 2 Diabetes Be Routinely Prescribed a Phosphodiesterase Type 5 Inhibitor? 2020 Jul 1
15 32401481 Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist. 2020 Jun 17 1
16 32502017 Effect of daily tadalafil on reported outcomes in patients with erectile dysfunction and depressive symptoms: STROBE, a case-control study. 2020 Jun 5 2
17 32542854 Efficacy and safety of tadalafil vs tamsulosin in lower urinary tract symptoms (LUTS) as a result of benign prostate hyperplasia (BPH)-open label randomised controlled study. 2020 Aug 1
18 32794708 Discovery of Evodiamine Derivatives as Highly Selective PDE5 Inhibitors Targeting a Unique Allosteric Pocket. 2020 Sep 10 2
19 30381900 Q817G mutation in phosphodiesterase type 5: Conformational analysis and dissociation profile of the inhibitor Tadalafil. 2019 Apr 2
20 30414862 Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma. 2019 Mar 1
21 30747070 Novel Pyrazolo[4, 3-c]Quinolin-3-One Derivatives as PDE5A Inhibitors. 2019 1
22 30901259 Tadalafil for the treatment of benign prostatic hyperplasia. 2019 Jun 1
23 31184029 [Safety of tadalafil in patients with cardiovascular comorbidities]. 2019 Apr 1
24 31208060 Safety Evaluation of Tadalafil Treatment for Fetuses with Early-Onset Growth Restriction (TADAFER): Results from the Phase II Trial. 2019 Jun 15 2
25 31214178 The Reversal of Immune Exclusion Mediated by Tadalafil and an Anti-tumor Vaccine Also Induces PDL1 Upregulation in Recurrent Head and Neck Squamous Cell Carcinoma: Interim Analysis of a Phase I Clinical Trial. 2019 1
26 31352710 The Effect of Daily Low Dose Tadalafil on Cerebral Perfusion and Cognition in Patients with Erectile Dysfunction and Mild Cognitive Impairment. 2019 Aug 31 1
27 31807426 An open-label, single-arm pilot study to evaluate the efficacy of daily low dose tadalafil on depression in patients with erectile dysfunction. 2019 Oct 1
28 28830281 Administration of daily 5 mg tadalafil improves endothelial function in patients with benign prostatic hyperplasia. 2018 Mar 1
29 29089445 Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects. 2018 Mar 1
30 29132113 Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5. 2018 Feb 5 1
31 29391766 Beneficial long term effect of a phosphodiesterase-5-inhibitor in cirrhotic portal hypertension: A case report with 8 years follow-up. 2018 Jan 21 1
32 29417353 Perioperative management with phosphodiesterase type 5 inhibitor and prostaglandin E1 for moderate portopulmonary hypertension following adult-to-adult living-donor liver transplantation: a case report. 2018 Feb 7 2
33 29920215 Analysis of short-term treatment with the phosphodiesterase type 5 inhibitor tadalafil on long bone development in young rats. 2018 Oct 1 2
34 30352768 Role of neuronal nitric oxide synthase (nNOS) in Duchenne and Becker muscular dystrophies - Still a possible treatment modality? 2018 Nov 2
35 30381311 TADAFER II: Tadalafil treatment for fetal growth restriction - a study protocol for a multicenter randomised controlled phase II trial. 2018 Oct 30 1
36 30504628 Characterization and Stability of Amorphous Tadalafil and Four Crystalline Polymorphs. 2018 2
37 30548639 Tadalafil: 15 years' journey in male erectile dysfunction and beyond. 2018 Dec 13 1
38 27101805 A randomized clinical trial investigating treatment choice in Chinese men receiving sildenafil citrate and tadalafil for treating erectile dysfunction. 2017 Jul-Aug 2
39 27338710 Adulteration of herbal sexual enhancers and slimmers: The wish for better sexual well-being and perfect body can be risky. 2017 Oct 2
40 27581752 In silico design of novel hERG-neutral sildenafil-like PDE5 inhibitors. 2017 Oct 1
41 28150511 Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development. 2017 Dec 7
42 28566262 Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular size and function - A multi-center, double-blind, randomized, placebo-controlled clinical trial - SERVE trial - Rational and design. 2017 Sep 15 1
43 28597769 A systematic review of transition studies of pulmonary arterial hypertension specific medications. 2017 Apr-Jun 1
44 28603047 Tadalafil induces antiproliferation, apoptosis, and phosphodiesterase type 5 downregulation in idiopathic pulmonary arterial hypertension in vitro. 2017 Sep 5 3
45 28932631 Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe). 2017 2
46 28964803 Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets. 2017 Dec 1 4
47 29202488 Acute tadalafil administration increases plasma fatty acids without changes in the inflammatory response in healthy men. 2017 1
48 29256125 Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction. 2017 1
49 25263347 LC-ESI-MS/MS analysis of phosphodiesterase-5 inhibitors and their analogues in foods and dietary supplements in Korea. 2016 1
50 26289211 Transdermal delivery of tadalafil using a novel formulation. 2016 Jun 1