RG7388

transformed mouse 3T3 cell double minute 2 ; Mus musculus







13 Article(s)
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1 34465864 PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression. 2022 Feb 1
2 34100216 Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells. 2021 Jun 2
3 34523337 Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation. 2021 Oct 4 7
4 32629830 Chemopreventive Agent 3,3'-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells. 2020 Jun 30 2
5 32806555 MDM2 Antagonists Induce a Paradoxical Activation of Erk1/2 through a P53-Dependent Mechanism in Dedifferentiated Liposarcomas: Implications for Combinatorial Strategies. 2020 Aug 12 1
6 30274984 Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib. 2019 Jan 1 1
7 30755442 MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors. 2019 May 1 1
8 31289443 MDM2 antagonists as a novel treatment option for acute myeloid leukemia: perspectives on the therapeutic potential of idasanutlin (RG7388). 2019 1
9 31311404 MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma. 2019 2
10 29857559 The Cellular p53 Inhibitor MDM2 and the Growth Factor Receptor FLT3 as Biomarkers for Treatment Responses to the MDM2-Inhibitor Idasanutlin and the MEK1 Inhibitor Cobimetinib in Acute Myeloid Leukemia. 2018 May 31 5
11 27353420 Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models. 2016 Jun 28 2
12 25832557 Inhibition of MDM2 by RG7388 confers hypersensitivity to X-radiation in xenograft models of childhood sarcoma. 2015 Aug 1
13 26998348 The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma. 2015 1