Pub. Date : 2021 Oct 4
PMID : 34523337
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation. | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 2 | RG7388 (Idasanutlin) is a potent inhibitor of oncoprotein murine double minute 2 (MDM2). | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 3 | RG7388 (Idasanutlin) is a potent inhibitor of oncoprotein murine double minute 2 (MDM2). | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 4 | RG7388 (Idasanutlin) is a potent inhibitor of oncoprotein murine double minute 2 (MDM2). | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 5 | RG7388 (Idasanutlin) is a potent inhibitor of oncoprotein murine double minute 2 (MDM2). | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 6 | Herein we investigated the feasibility of developing 18F-labeled RG7388 as a radiotracer for imaging MDM2 expression in tumors with positron emission tomography (PET). | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |
| 7 | Our results suggest that RG7388 is a promising molecular scaffold for 18F-labeled probe development for MDM2. | RG7388 | transformed mouse 3T3 cell double minute 2 | Mus musculus |