Title : PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.

Pub. Date : 2022 Feb

PMID : 34465864






1 Functional Relationships(s)
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1 Furthermore, combination therapy with a JAK3 inhibitor (tofacitinib) and a MDM2 inhibitor (idasanutlin) reduces the Phf6 KO and JAK3M511I leukemia burden in vivo. RG7388 transformed mouse 3T3 cell double minute 2 Mus musculus