Superoxides

pleckstrin ; Homo sapiens







80 Article(s)
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51 12225397 GM-CSF induces expression of gp91phox and stimulates retinoic acid-induced p47phox expression in human myeloblastic leukemia cells. 2002 Jun 1
52 12456638 The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase. 2002 Dec 2 2
53 11145703 Protein kinase C zeta phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst. 2001 Jan 15 1
54 11348868 Increased NAD(P)H oxidase and reactive oxygen species in coronary arteries after balloon injury. 2001 May 2
55 11397907 Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations. 2001 Jun 1
56 11705402 A fusion protein between rac and p67phox (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components. 2001 Nov 20 1
57 11726431 The effects of lidocaine on superoxide production and p47 Phox translocation in opsonized zymosan-activated neutrophils. 2001 Dec 2
58 10788501 Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase. 2000 May 5 4
59 10400704 Priming of human neutrophil respiratory burst by granulocyte/macrophage colony-stimulating factor (GM-CSF) involves partial phosphorylation of p47(phox). 1999 Jul 16 2
60 10559253 Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase. 1999 Nov 19 2
61 9461621 Anionic amphiphile-independent activation of the phagocyte NADPH oxidase in a cell-free system by p47phox and p67phox, both in C terminally truncated forms. Implication for regulatory Src homology 3 domain-mediated interactions. 1998 Feb 13 5
62 9624128 Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking". 1998 Jun 19 1
63 9642219 Regulation of the neutrophil respiratory burst oxidase. Identification of an activation domain in p67(phox). 1998 Jul 3 1
64 9804763 p40(phox) is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase. Implication of a protein kinase c-type kinase in the phosphorylation process. 1998 Nov 13 1
65 8551399 Genotype-dependent variability in flow cytometric evaluation of reduced nicotinamide adenine dinucleotide phosphate oxidase function in patients with chronic granulomatous disease. 1996 Jan 1
66 8663333 Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox. 1996 Jul 19 2
67 8703027 Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase. 1996 Sep 6 2
68 8798426 NADPH oxidase activity is independent of p47phox in vitro. 1996 Sep 13 1
69 8939991 The cytosolic component p47(phox) is not a sine qua non participant in the activation of NADPH oxidase but is required for optimal superoxide production. 1996 Nov 29 4
70 7658912 PGI2 analogue, sodium beraprost, suppresses superoxide generation in human neutrophils by inhibiting p47phox phosphorylation. 1995 1
71 8028054 Superoxide production by neutrophils from trauma patients: regulation of NADPH oxidase activity. 1994 Jul 1
72 8167697 Is the IFN-gamma-induced enhancement of superoxide production in CGD-phagocytes caused by increased expression of the p47-phox cytosolic protein. 1993 1
73 8167728 Chronic granulomatous disease: towards gene therapy. 1993 1
74 8250232 A generally applicable ELISA for the detection and quantitation of the cytosolic factors of NADPH-oxidase activation in neutrophils. 1993 Oct 1
75 8395827 Combination of arachidonic acid and guanosine 5'-O-(3-thiotriphosphate) induce translocation of rac p21s to membrane and activation of NADPH oxidase in a cell-free system. 1993 Aug 31 1
76 1313435 Effects of antagonists of protein phosphatases on superoxide release by neutrophils. 1992 Mar 25 2
77 1316893 Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins. 1992 May 25 1
78 1325210 Restoration of superoxide generation to a chronic granulomatous disease-derived B-cell line by retrovirus mediated gene transfer. 1992 Sep 1 1
79 1848559 Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components. 1991 Mar 25 2
80 2265254 Immunochemical and electrophoretic analyses of phosphorylated native and recombinant neutrophil oxidase component p47-phox. 1990 Dec 15 1