Tyrosine

CD4 molecule ; Homo sapiens







128 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33791292 How the Discovery of the CD4/CD8-p56lck Complexes Changed Immunology and Immunotherapy. 2021 1
2 34598062 Discovery of a novel anti PD-L1 X TIGIT bispecific antibody for the treatment of solid tumors. 2021 1
3 30382432 MEG3 modulates TIGIT expression and CD4 + T cell activation through absorbing miR-23a. 2019 Apr 1
4 30541842 A Coreceptor-Mimetic Peptide Enhances the Potency of V3-Glycan Antibodies. 2019 Mar 1 1
5 31539562 Nitric oxide stimulates a PKC-Src-Akt signaling axis which increases human immunodeficiency virus type 1 replication in human T lymphocytes. 2019 Dec 1 1
6 31792452 Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. 2019 Dec 1
7 29410624 CP-25 Attenuates the Activation of CD4+ T Cells Stimulated with Immunoglobulin D in Human. 2018 1
8 27389109 Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry. 2016 Aug 1
9 27578921 Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling. 2016 1
10 24569807 Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity. 2014 Feb 25 3
11 23152518 Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression. 2013 Feb 1
12 24048955 CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways. 2013 Dec 3
13 21482738 Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis. 2011 May 15 3
14 21763489 The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide. 2011 Jul 29 1
15 18424715 Conversion of tyrosine to the inflammation-associated analog 3'-nitrotyrosine at either TCR- or MHC-contact positions can profoundly affect recognition of the MHC class I-restricted epitope of lymphocytic choriomeningitis virus glycoprotein 33 by CD8 T cells. 2008 May 1 1
16 18619676 Defect in TCR-CD3zeta signaling mediates T cell hypo-responsiveness in mesenteric lymph node. 2008 Aug 1
17 17392283 Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance. 2007 Jun 1 1
18 17726154 Modulation of CD1d-restricted NKT cell responses by CD4. 2007 Dec 1
19 17901336 Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. 2007 Sep 28 2
20 16684890 Altered proximal T cell receptor (TCR) signaling in human CD4+CD25+ regulatory T cells. 2006 Jul 1
21 17082567 Cutting edge: CD4 is the receptor for the tick saliva immunosuppressor, Salp15. 2006 Nov 15 1
22 15585656 Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2. 2005 Apr 1 2
23 12517957 Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. 2003 Jan 15 2
24 12794125 A model for antigen-specific T-cell anergy: displacement of CD4-p56(lck) signalosome from the lipid rafts by a soluble, dimeric peptide-MHC class II chimera. 2003 Jun 15 1
25 12887918 Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120. 2003 Jul 25 1
26 12938237 The activation of Csk by CD4 interferes with TCR-mediated activatory signaling. 2003 Sep 1
27 11694532 Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction. 2002 Jan 18 1
28 11744048 Age-related impairment of human T lymphocytes' activation: specific differences between CD4(+) and CD8(+) subsets. 2002 Feb 1
29 12055630 Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation. 2002 Jul 1
30 12121665 Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. 2002 Jun 1
31 12171035 p56(lck) Controls phosphorylation of filamin (ABP-280) and regulates focal adhesion kinase (pp125(FAK)). 2002 1
32 11292262 The "early' CD4+CD8+ stage of thymocte differentiation hallmarks the end of a strong positive correlation between extracellular matrix receptor expression and protein tyrosine phosphorylation. 2001 Feb 1
33 11389026 Generation and biochemical analysis of human effector CD4 T cells: alterations in tyrosine phosphorylation and loss of CD3zeta expression. 2001 Jun 15 2
34 11509608 Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome. 2001 Sep 1 1
35 10744646 Defective p56Lck activity in T cells from an adult patient with idiopathic CD4+ lymphocytopenia. 2000 Apr 1
36 10938094 A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry. 2000 Oct 27 2
37 10202115 Apoptosis induced by crosslinking of CD4 on activated human B cells. 1999 Apr 10 1
38 10356363 Human glomerular epithelial cell express CD4 and interaction with gp120 protein promotes PYK2 tyrosine phosphorylation. 1999 May 1
39 10358157 Inhibition of tyrosine kinase activation blocks the down-regulation of CXC chemokine receptor 4 by HIV-1 gp120 in CD4+ T cells. 1999 Jun 15 1
40 10400642 Role of protein kinase C in signal attenuation following T cell receptor engagement. 1999 Jul 16 1
41 10438903 Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells. 1999 Aug 15 1
42 10458777 Obligatory cross-talk with the tyrosine kinases assembled with the TCR/CD3 complex in CD4 signal transduction. 1999 Aug 2
43 10477559 Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. 1999 Sep 15 3
44 10477581 SLP-76 binding to p56lck: a role for SLP-76 in CD4-induced desensitization of the TCR/CD3 signaling complex. 1999 Sep 15 1
45 10586033 Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes. 1999 Dec 15 1
46 10851550 [Deficiency of the CD3-TCR signal pathway in three patients with idiopathic CD4+ lymphocytopenia]. 1999 1
47 9584148 Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor. 1998 May 18 1
48 9710204 Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc. 1998 Aug 1
49 9751431 Effect of age on mitogen induced protein tyrosine phosphorylation in human T cell and its subsets: down-regulation of tyrosine phosphorylation of ZAP-70. 1998 Aug 1 2
50 9825124 Synthesis and biological activity of chelator-peptide T conjugates. 1998 Oct 1