Title : Cutting edge: CD4 is the receptor for the tick saliva immunosuppressor, Salp15.

Pub. Date : 2006 Nov 15

PMID : 17082567






1 Functional Relationships(s)
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1 Upon binding to CD4, Salp15 inhibits the subsequent TCR ligation-induced T cell signaling at the earliest steps including tyrosine phosphorylation of the Src kinase Lck, downstream effector proteins, and lipid raft reorganization. Tyrosine CD4 molecule Homo sapiens