Serine

huntingtin ; Homo sapiens







19 Article(s)
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1 32805086 Site-Specific Phosphorylation of Huntingtin Exon 1 Recombinant Proteins Enabled by the Discovery of Novel Kinases. 2021 Jan 5 1
2 32941796 Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila. 2021 Apr 1
3 30538129 High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry. 2019 Feb 8 1
4 24334607 Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions. 2014 May 1 1
5 24505464 Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity. 2014 1
6 25099302 BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. 2014 Dec 3
7 22999956 Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties. 2012 Nov 23 1
8 18992820 Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments. 2009 Feb 1
9 19860865 Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease. 2009 Oct 27 1
10 20064390 Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. 2009 Dec 24 1
11 18573880 Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. 2008 Sep 1
12 18615096 Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. 2008 Aug 6 1
13 18772195 Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons. 2008 Dec 15 1
14 17611284 Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons. 2007 Jul 4 2
15 15809304 Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment. 2005 Jun 10 1
16 16471265 [Huntington's disease: intracellular signaling pathways and neuronal death]. 2005 1
17 14725621 The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin. 2004 Jan 4
18 12062094 The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. 2002 Jun 1
19 9466992 Huntingtin interacts with cystathionine beta-synthase. 1998 Mar 1