Title : Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation.

Pub. Date : 2008 Sep

PMID : 18573880






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 This requires profilin"s G-actin binding activity and its direct interaction with Htt, which are both inhibited by the ROCK1-mediated phosphorylation of profilin at Ser-137. Serine huntingtin Homo sapiens