ibrutinib

Bruton tyrosine kinase ; Homo sapiens







664 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 35608822 Selinexor combined with ibrutinib demonstrates tolerability and safety in advanced B-cell malignancies: A phase I study. 2022 May 24 1
52 35628931 Bruton's Kinase Inhibitors for the Treatment of Immunological Diseases: Current Status and Perspectives. 2022 May 16 1
53 31949019 Low-dose Btk inhibitors selectively block platelet activation by CLEC-2. 2021 Jan 1 1
54 32336682 Stem cell factor is implicated in microenvironmental interactions and cellular dynamics of chronic lymphocytic leukemia. 2021 Mar 1 1
55 32640487 BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID-19 therapy. 2021 Jan 1
56 32683672 Ibrutinib for improved chimeric antigen receptor T-cell production for chronic lymphocytic leukemia patients. 2021 Jan 15 3
57 32855274 Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines. 2021 Oct 1 1
58 32961571 Ibrutinib Suppresses Early Megakaryopoiesis but Enhances Proplatelet Formation. 2021 Feb 1
59 32978866 Case of hepatitis B virus reactivation after ibrutinib therapy in which the patient remained negative for hepatitis B surface antigens throughout the clinical course. 2021 Feb 1
60 32979005 Chemoproteomic Profiling of an Ibrutinib Analogue Reveals its Unexpected Role in DNA Damage Repair. 2021 Jan 5 3
61 33011863 ALK-positive histiocytosis associated with chronic lymphocytic leukaemia/small lymphocytic lymphoma: a multitarget response under ibrutinib. 2021 Apr 1
62 33171493 miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors. 2021 May 6 1
63 33190294 Predictive significance of selected gene mutations in relapsed and refractory chronic lymphocytic leukemia patients treated with ibrutinib. 2021 Mar 2
64 33216986 Incorporating acalabrutinib, a selective next-generation Bruton tyrosine kinase inhibitor, into clinical practice for the treatment of haematological malignancies. 2021 Apr 3
65 33272709 Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML. 2021 Jan 1
66 33273263 Dabigatran in ibrutinib-treated patients with atrial fibrillation and chronic lymphocytic leukemia: experience of three cases. 2021 Mar 1 1
67 33273682 CXCR4 in Waldenström's Macroglobulinema: chances and challenges. 2021 Feb 2
68 33328281 Relevance of the Bruton Tyrosine Kinase as a Target for COVID-19 Therapy. 2021 Apr 1
69 33419778 Follicular Lymphoma-associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation. 2021 Apr 15 2
70 33434619 Orally effective FDA-approved protein kinase targeted covalent inhibitors (TCIs). 2021 Mar 1
71 33441177 Observations on the use of Bruton's tyrosine kinase inhibitors in SAR-CoV-2 and cancer. 2021 Jan 13 2
72 33539945 Ibrutinib in combination with nab-paclitaxel and gemcitabine for first-line treatment of patients with metastatic pancreatic adenocarcinoma: phase III RESOLVE study. 2021 May 1
73 33552659 Impact of Adherence to Ibrutinib on Clinical Outcomes in Real-World Patients With Chronic Lymphocytic Leukemia. 2021 Jan-Feb 2
74 33567947 Ibrutinib-induced acute kidney injury via interstitial nephritis. 2021 Dec 1
75 33570628 Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2. 2021 Jan 12 1
76 33570649 Overcoming resistance to targeted therapies in chronic lymphocytic leukemia. 2021 Jan 12 1
77 33602908 Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication. 2021 Feb 18 1
78 33640875 Interdisciplinary approach to the current management of chronic lymphocytic leukemia 2021 Feb 28 1
79 33640903 Inhibition of Bruton's tyrosine kinase as a therapeutic strategy for chemoresistant oral squamous cell carcinoma and potential suppression of cancer stemness. 2021 Feb 27 1
80 33663302 A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib. 2021 Aug 2
81 33669329 Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström's Macroglobulinemia. 2021 Feb 16 1
82 33688166 Zanubrutinib (BGB-3111), a Second-Generation Selective Covalent Inhibitor of Bruton's Tyrosine Kinase and Its Utility in Treating Chronic Lymphocytic Leukemia. 2021 2
83 33718939 Managing chronic lymphocytic leukemia in 2020: an update on recent clinical advances with a focus on BTK and BCL-2 inhibitors. 2021 2
84 33730585 Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma. 2021 Mar 16 3
85 33730844 Phase II study of acalabrutinib in ibrutinib-intolerant patients with relapsed/refractory chronic lymphocytic leukemia. 2021 Sep 1 1
86 33734339 Treon SP, Castillo JJ, Skarbnik AP, et al. The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients. Blood. 2020;135(21):1912-1915. 2021 Mar 18 1
87 33735912 MARCKS affects cell motility and response to BTK inhibitors in CLL. 2021 Aug 19 1
88 33740218 Population Pharmacokinetics of Ibrutinib in Healthy Adults. 2021 May 1
89 33740548 Emerging small-molecule inhibitors of the Bruton's tyrosine kinase (BTK): Current development. 2021 May 5 1
90 33754642 Phase 2 study of ibrutinib in classic and variant hairy cell leukemia. 2021 Jun 24 1
91 33760219 Bruton's agammaglobulinemia tyrosine kinase (Btk) regulates TPA‑induced breast cancer cell invasion via PLCγ2/PKCβ/NF‑κB/AP‑1‑dependent matrix metalloproteinase‑9 activation. 2021 May 1
92 33761747 Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry. 2021 Apr 7 2
93 33772839 High-throughput liquid chromatography/electrospray ionization-tandem mass spectrometry method using in-source collision-induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma. 2021 Aug 1
94 33775465 Revisiting Richter transformation in the era of novel CLL agents. 2021 Sep 1
95 33796237 The evolving role of Bruton's tyrosine kinase inhibitors in chronic lymphocytic leukemia. 2021 2
96 33799484 Relapsed Mantle Cell Lymphoma: Current Management, Recent Progress, and Future Directions. 2021 Mar 14 1
97 33807411 Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells. 2021 Mar 31 2
98 33809580 Novel Agents in Chronic Lymphocytic Leukemia: New Combination Therapies and Strategies to Overcome Resistance. 2021 Mar 16 2
99 33810025 Aromatic Rings as Molecular Determinants for the Molecular Recognition of Protein Kinase Inhibitors. 2021 Mar 22 2
100 33851389 Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): Targeting Pathomechanisms with Bruton Tyrosine Kinase Inhibitors. 2021 Nov 2