Title : Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair.

Pub. Date : 2017 Apr 4

PMID : 28376831






1 Functional Relationships(s)
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1 CONCLUSIONS: In EOC, low let-7e leads to activation of BRCA1 and Rad51 expression and subsequent enhancement of DSB repair, which in turn results in cisplatin-resistance. Cisplatin BRCA1 DNA repair associated Homo sapiens