Doxorubicin

BRCA1 DNA repair associated ; Homo sapiens







46 Article(s)
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1 35242827 BRCA1/2 Mutations and Cardiovascular Function in Breast Cancer Survivors. 2022 4
2 33536037 Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin. 2021 Feb 3 1
3 33896588 Hypersensitivity to platinum salts according to BRCA status in ovarian cancer: A retrospective analysis of clinical outcomes and systematic review of literature. 2021 Jul 1
4 32331767 Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency. 2020 Jun 1
5 32876438 Potential Doxorubicin-Mediated Dual-Targeting Chemotherapy in FANC/BRCA-Deficient Tumors via Modulation of Cellular Formaldehyde Concentration. 2020 Oct 19 2
6 33074587 EBV-encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1. 2020 Nov 1
7 31215481 MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer. 2019 Jun 18 3
8 31411802 BRCA mutation frequency and clinical features of ovarian cancer patients: A report from a Chinese study group. 2019 Nov 1
9 31511498 Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response. 2019 Sep 11 1
10 29298688 Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations. 2018 Jan 3 1
11 29686231 Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1. 2018 Apr 23 1
12 29784019 The PARP inhibitor olaparib potentiates the effect of the DNA damaging agent doxorubicin in osteosarcoma. 2018 May 21 1
13 29929045 Regulation of DNA repair in the absence of classical non-homologous end joining. 2018 Aug 1
14 30028120 Overcoming Chemoresistance in Cancer via Combined MicroRNA Therapeutics with Anticancer Drugs Using Multifunctional Magnetic Core-Shell Nanoparticles. 2018 Aug 15 1
15 28881292 Exceptionally high UBE2C expression is a unique phenomenon in basal-like type breast cancer and is regulated by BRCA1. 2017 Nov 2
16 26785283 Ovarian cancer treatment in mutation carriers/BRCAness. 2016 Oct 1
17 27113739 Neo-adjuvant doxorubicin and cyclophosphamide followed by paclitaxel in triple-negative breast cancer among BRCA1 mutation carriers and non-carriers. 2016 May 1
18 27555886 Cytotoxic and targeted therapy for hereditary cancers. 2016 2
19 24996439 The Fanconi anemia/BRCA pathway is involved in DNA interstrand cross-link repair of adriamycin-resistant leukemia cells. 2015 Mar 2
20 25993149 Chemotherapy for Patients with BRCA1 and BRCA2-Mutated Ovarian Cancer: Same or Different? 2015 1
21 26027929 MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy. 2015 Jun 9 2
22 25337234 Effect of adriamycin on BRCA1 and PARP-1 expression in MCF-7 breast cancer cells. 2014 7
23 23376355 3,3'-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway. 2013 Apr 1
24 23548133 Systemic treatment for hereditary cancers: a 2012 update. 2013 Apr 1 1
25 23670255 BRCA1 and p53 regulate critical prostate cancer pathways. 2013 Sep 2
26 22807977 BRCA1 protein levels and PIK3CA mutations as predictive biomarkers for response to neoadjuvant chemotherapy in locally advanced breast cancer: An exploratory analysis. 2012 Jul 1
27 22832221 Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription. 2012 2
28 21700680 BRCA1 loss induces GADD153-mediated doxorubicin resistance in prostate cancer. 2011 Aug 3
29 21835933 BRCA mutation status and determinant of outcome in women with recurrent epithelial ovarian cancer treated with pegylated liposomal doxorubicin. 2011 Oct 1
30 21864706 BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage. 2011 Dec 6
31 21945552 A high response rate to liposomal doxorubicin is seen among women with BRCA mutations treated for recurrent epithelial ovarian cancer. 2011 Dec 1
32 19593673 Altered expression of proliferation-inducing and proliferation-inhibiting genes might contribute to acquired doxorubicin resistance in breast cancer cells. 2009 1
33 19820363 Family history of cancer rather than p53 status predicts efficacy of pegylated liposomal doxorubicin and oxaliplatin in relapsed ovarian cancer. 2009 Aug 1
34 17492376 Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancers. 2008 Mar 1
35 15607317 Development and applications of a real-time quantitative RT-PCR method (QRT-PCR) for BRCA1 mRNA. 2005 Jan 1
36 12684687 The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells. 2003 May 1
37 12698198 BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells. 2003 Apr 22 1
38 12024039 BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. 2002 Jun 1
39 12170778 BRCA1 transcriptionally regulates damaged DNA binding protein (DDB2) in the DNA repair response following UV-irradiation. 2002 Mar-Apr 1
40 11295099 Regulation of BRCA1 and BRCA2 transcript in response to cisplatin, adriamycin, taxol and ionising radiation is correlated to p53 functional status in ovarian cancer cell lines. 2001 May-Jun 1
41 10764811 Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor. 2000 Jun 16 1
42 10884389 Repression of BRCA1 through a feedback loop involving p53. 2000 Oct 13 3
43 10196224 Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. 1999 Apr 16 2
44 10344722 Coordinate alterations in the expression of BRCA1, BRCA2, p300, and Rad51 in response to genotoxic and other stresses in human prostate cancer cells. 1999 Jun 15 1
45 9619832 Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents. 1998 Apr 30 7
46 9679765 Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation. 1998 Aug 12 2