Dexmedetomidine

BCL2, apoptosis regulator ; Rattus norvegicus







30 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35459107 Dexmedetomidine improved one-lung ventilation-induced cognitive dysfunction in rats. 2022 Apr 23 1
2 35527005 Dexmedetomidine attenuates acute stress-induced liver injury in rats by regulating the miR-34a-5p/ROS/JNK/p38 signaling pathway. 2022 1
3 33220608 Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway. 2021 Jan 2
4 33280824 The Protective Effects of Dexmedetomidine Preconditioning on Hepatic Ischemia/Reperfusion Injury in Rats. 2021 Jan-Feb 1
5 34121490 Protective effect of dexmedetomidine on neuronal hypoxic injury through inhibition of miR-134. 2021 Dec 3
6 34135573 High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons. 2021 1
7 31635678 The Role of Janus Kinase/Signal Transducer and Activator of Transcription Signalling on Preventing Intestinal Ischemia/Reperfusion Injury with Dexmedetomidine. 2020 May 1 1
8 31680420 Dexmedetomidine post-treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF-1α signalling. 2020 Jan 1
9 32034118 The Effects of Dexmedetomidine in a Rat Model of Sepsis-Induced Lung Injury are Mediated Through the Adenosine Monophosphate-Activated Protein Kinase (AMPK)/Silent Information Regulator 1 (SIRT1) Pathway. 2020 Feb 8 1
10 32407987 Dexmedetomidine pretreatment protects the heart against apoptosis in ischemia/reperfusion injury in diabetic rats by activating PI3K/Akt signaling in vivo and in vitro. 2020 Jul 2
11 32419697 Dexmedetomidine Attenuates Glutamate-Induced Cytotoxicity by Inhibiting the Mitochondrial-Mediated Apoptotic Pathway. 2020 May 18 1
12 32655771 Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway. 2020 1
13 33173983 Dexmedetomidine reduces ventilator-induced lung injury via ERK1/2 pathway activation. 2020 Dec 1
14 30655009 [Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats]. 2019 Mar - Apr 1
15 31220473 Dexmedetomidine protects neurons from kainic acid-induced excitotoxicity by activating BDNF signaling. 2019 Oct 2
16 31308624 Dexmedetomidine protects PC12 cells from lidocaine-induced cytotoxicity via downregulation of Stathmin 1. 2019 1
17 31511215 [Dexmedetomidine hydrochloride up-regulates expression of hypoxia inducible factor-1α to alleviate renal ischemiareperfusion injury in diabetic rats]. 2019 Aug 30 2
18 29693126 Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression. 2018 Jun 1
19 29749492 Locomotor activity of rats with SCI is improved by dexmedetomidine by targeting the expression of inflammatory factors. 2018 Jul 1
20 30402501 Effects of Dexmedetomidine Postconditioning on Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Role of the PI3K/Akt-Dependent Signaling Pathway. 2018 2
21 27959438 Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats. 2017 Jan 1
22 28436683 Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b. 2017 Jul 1
23 28463790 Dexmedetomidine inhibits activation of the MAPK pathway and protects PC12 and NG108-15 cells from lidocaine-induced cytotoxicity at its maximum safe dose. 2017 Jul 1
24 27069541 Dexmedetomidine alleviates postoperative cognitive dysfunction by inhibiting neuron excitation in aged rats. 2016 1
25 27221008 Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury. 2016 Jul 1
26 27571870 Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus. 2016 Oct 2
27 26622369 Protective effects of dexmedetomidine on intestinal ischemia-reperfusion injury. 2015 Aug 1
28 25026397 Both JNK and P38 MAPK pathways participate in the protection by dexmedetomidine against isoflurane-induced neuroapoptosis in the hippocampus of neonatal rats. 2014 Aug 1
29 20003127 Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. 2010 Jul 1
30 12538207 The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. 2003 Feb 1