Title : The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats.

Pub. Date : 2003 Feb

PMID : 12538207






1 Functional Relationships(s)
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1 In animals treated with dexmedetomidine, the expression of Bcl-2 and Mdm-2 was larger compared with control (68% and 210%, respectively) or sham-operated (110% and 180%, respectively) animals. Dexmedetomidine BCL2, apoptosis regulator Rattus norvegicus