pyrazolo(1,5-a)pyrimidine

cyclin dependent kinase 2 ; Homo sapiens







8 Article(s)
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Title
Pub. Year
#Total Relationships
1 34688130 Synthesis of a new series of pyrazolo[1,5-a]pyrimidines as CDK2 inhibitors and anti-leukemia. 2021 Dec 2
2 30682722 Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity. 2019 May 2
3 28039837 Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines. 2017 Jan 27 4
4 23157414 Quantum mechanical scoring: structural and energetic insights into cyclin-dependent kinase 2 inhibition by pyrazolo[1,5-a]pyrimidines. 2013 Mar 1
5 23864105 An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors. 2013 Sep 2
6 21080703 A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. 2010 Dec 23 1
7 17904366 Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors. 2007 Nov 15 1
8 15686876 Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2. 2005 Feb 15 3