Title : Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors.

Pub. Date : 2007 Nov 15

PMID : 17904366






1 Functional Relationships(s)
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1 From the in-vitro and cell-based analysis, the pyrazolo[1,5-a]pyrimidine core (represented by 9) emerged as the superior core for further elaboration in the identification of novel CDK2 inhibitors. pyrazolo(1,5-a)pyrimidine cyclin dependent kinase 2 Homo sapiens