Fatty Acids

peroxisome proliferator activated receptor alpha ; Mus musculus







441 Article(s)
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51 32202512 Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism. 2020 May 1 1
52 32206109 NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease. 2020 4
53 32300166 Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity. 2020 Apr 16 2
54 32365470 Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids. 2020 Apr 29 1
55 32373236 Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-α pathway-dependent fatty acid oxidation. 2020 2
56 32452329 Co-Administration of Soluble Fibres and Lactobacillus casei NCDC19 Fermented Milk Prevents Adiposity and Insulin Resistance Via Modulation of Lipid Mobilization Genes in Diet-Induced Obese Mice. 2020 1
57 32457304 A Gilbert syndrome-associated haplotype protects against fatty liver disease in humanized transgenic mice. 2020 May 26 2
58 32463484 Protective and Detrimental Roles of p38α Mitogen-Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease. 2020 Sep 1
59 32549364 Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice. 2020 Jun 15 1
60 32559625 The anti-inflammatory and immune-modulatory effects of OEA limit DSS-induced colitis in mice. 2020 Sep 1
61 32577122 TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter. 2020 1
62 32717288 Targeting NFATc4 attenuates non-alcoholic steatohepatitis in mice. 2020 Dec 2
63 32912335 SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2. 2020 Sep 10 1
64 32966473 Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance via activation of PPARα/γ in mice. 2020 Sep 23 1
65 33326461 The pharmacodynamic and differential gene expression analysis of PPAR α/δ agonist GFT505 in CDAHFD-induced NASH model. 2020 1
66 33391822 Short- and long-term effects of perinatal phthalate exposures on metabolic pathways in the mouse liver. 2020 2
67 33425805 Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease. 2020 1
68 30278189 Enhancement of fear learning in PPARα knockout mice. 2019 Feb 1 2
69 30283077 Ascorbic acid inhibits visceral obesity and nonalcoholic fatty liver disease by activating peroxisome proliferator-activated receptor α in high-fat-diet-fed C57BL/6J mice. 2019 Aug 3
70 30341732 Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice. 2019 Jan 2
71 30677905 Prenatal exposure to ambient fine particulate matter induces dysregulations of lipid metabolism in adipose tissue in male offspring. 2019 Mar 20 1
72 30733541 MD001, a Novel Peroxisome Proliferator-activated Receptor α/γ Agonist, Improves Glucose and Lipid Metabolism. 2019 Feb 7 1
73 30789748 Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. 2019 Apr 1 2
74 30813654 Lonicera caerulea Extract Attenuates Non-Alcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Hepatocytes and in High Fat Diet-Fed Mice. 2019 Feb 26 2
75 30866796 Transcriptional profiling of PPARα-/- and CREB3L3-/- livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα. 2019 Mar 11 1
76 30968022 Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate but Does Not Change Cardiomyocyte Number in Infant Mice. 2019 1
77 31033195 Bromide alleviates fatty acid-induced lipid accumulation in mouse primary hepatocytes through the activation of PPARα signals. 2019 Jun 1
78 31062244 Maternal exposure to perfluorooctanoic acid (PFOA) causes liver toxicity through PPAR-α pathway and lowered histone acetylation in female offspring mice. 2019 Jun 2
79 31064103 Fermented Cordyceps militaris Extract Prevents Hepatosteatosis and Adipocyte Hypertrophy in High Fat Diet-Fed Mice. 2019 May 6 1
80 31102342 PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis. 2019 May 1
81 31211621 Mouse trefoil factor 3 ameliorated high-fat-diet-induced hepatic steatosis via increasing peroxisome proliferator-activated receptor-α-mediated fatty acid oxidation. 2019 Sep 1 3
82 31533003 The role of Ap2a2 in PPARα-mediated regulation of lipolysis in adipose tissue. 2019 Dec 1
83 31581697 Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic Mice. 2019 Oct 2 2
84 31766193 Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate. 2019 Nov 13 1
85 28871336 Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity. 2018 Jan 1
86 28903946 PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice. 2018 Jan 1 3
87 29146411 Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha. 2018 Jan 2
88 29208699 Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1. 2018 Feb 1
89 29318455 4',6-Dimethoxyisoflavone-7-O-β-D-glucopyranoside (wistin) is a peroxisome proliferator-activated receptor α (PPARα) agonist in mouse hepatocytes. 2018 Sep 1
90 29350678 PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis. 2018 Jan 19 2
91 29364658 Metabonomics Indicates Inhibition of Fatty Acid Synthesis, β-Oxidation, and Tricarboxylic Acid Cycle in Triclocarban-Induced Cardiac Metabolic Alterations in Male Mice. 2018 Feb 14 1
92 29409330 Bifidobacteria and its rice fermented products on diet induced obese mice: analysis of physical status, serum profile and gene expressions. 2018 Apr 25 1
93 29422939 Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. 2018 2
94 29500923 Regulation of hypoxia inducible factor/prolyl hydroxylase binding domain proteins 1 by PPARα and high salt diet. 2018 Mar 28 2
95 29626530 High-fat diet affects gut nutrients transporters in hypo and hyperthyroid mice by PPAR-a independent mechanism. 2018 Jun 1 1
96 29764990 IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. 2018 May 15 1
97 29772707 PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism. 2018 May 16 1
98 30012602 Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory. 2018 Jul 31 2
99 30135326 Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation. 2018 Nov 1 2
100 30158201 Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice. 2018 Nov 1