Title : IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.

Pub. Date : 2018 May 15

PMID : 29764990






1 Functional Relationships(s)
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1 This resulted in an increased abundance of these miRNA families in the liver and, consequently, a decreased abundance of their targets, which included peroxisome proliferator-activated receptor alpha (PPARalpha) and the deacetylase sirtuin 1 (SIRT1), regulators of fatty acid oxidation and triglyceride lipolysis. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus