Glucose

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peroxisome proliferator activated receptor alpha ; Mus musculus







125 Article(s)
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101 16123338 Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. 2005 Sep 2
102 16203912 Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization. 2005 Oct 11 4
103 14670991 Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux. 2004 Mar 4
104 14670996 Peroxisome proliferator-activated receptor-alpha deficiency does not alter insulin sensitivity in mice maintained on regular or high-fat diet: hyperinsulinemic-euglycemic clamp studies. 2004 Apr 2
105 14688286 Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short term fast. 2004 Mar 5 2
106 14982965 A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice. 2004 Jun 1
107 15001458 Modulation of PPARalpha expression and inflammatory interleukin-6 production by chronic glucose increases monocyte/endothelial adhesion. 2004 May 4
108 15232616 PPARalpha governs glycerol metabolism. 2004 Jul 2
109 15258145 A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects. 2004 Sep 24 1
110 15448592 Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice. 2004 Oct 1
111 12628477 Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation. 2003 Mar 1 2
112 12676649 Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice. 2003 May 1
113 12730403 Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells. 2003 May 1
114 11734553 A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. 2002 Feb 8 2
115 11781357 The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. 2002 Jan 3
116 12023878 Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin. 2002 Jun 1 1
117 12176975 Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production. 2002 Dec 27 5
118 12181123 Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator. 2002 Sep 3
119 12401884 AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. 2002 Nov 1
120 11306606 PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice. 2001 Apr 2
121 11723064 PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance. 2001 Dec 3
122 11735249 Responses of insulin-like growth factor (IGF)-I and IGF-binding proteins to nutritional status in peroxisome proliferator-activated receptor-alpha knockout mice. 2001 Oct 2
123 10634806 Differential regulation of macrophage peroxisome proliferator-activated receptor expression by glucose : role of peroxisome proliferator-activated receptors in lipoprotein lipase gene expression. 2000 Jan 1
124 11118287 PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver. 2000 Dec 20 2
125 10377130 Effect of peroxisome proliferator-activated receptor alpha activators on tumor necrosis factor expression in mice during endotoxemia. 1999 Jul 1