Glucose

peroxisome proliferator activated receptor alpha ; Mus musculus







125 Article(s)
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1 34757855 PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice. 2022 Apr 1
2 35163893 A Multitarget Approach to Evaluate the Efficacy of Aquilaria sinensis Flower Extract against Metabolic Syndrome. 2022 Jan 19 1
3 35222033 Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression. 2022 1
4 33758172 Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver. 2021 Mar 23 1
5 33813880 Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance. 2021 May 1 4
6 34240660 14-Deoxy-11,12-Didehydroandrographolide Ameliorates Glucose Intolerance Enhancing the LKB1/AMPK[Formula: see text]/TBC1D1/GLUT4 Signaling Pathway and Inducing GLUT4 Expression in Myotubes and Skeletal Muscle of Obese Mice. 2021 1
7 34244236 PPARα Agonist Fenofibrate Enhances Cancer Vaccine Efficacy. 2021 Sep 1 1
8 34380027 GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK. 2021 Aug 10 1
9 34551152 Deletion of pleiotrophin impairs glucose tolerance and liver metabolism in pregnant mice: Moonlighting role of glycerol kinase. 2021 Oct 1
10 34901001 PPARβ/δ Agonist Alleviates Diabetic Osteoporosis via Regulating M1/M2 Macrophage Polarization. 2021 1
11 32292119 MicroRNA-409-5p promotes retinal neovascularization in diabetic retinopathy. 2020 Jun 2
12 30733541 MD001, a Novel Peroxisome Proliferator-activated Receptor α/γ Agonist, Improves Glucose and Lipid Metabolism. 2019 Feb 7 3
13 30765336 Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein. 2019 May 1
14 31270056 [Conjugated linoleic acid improves glucose and lipid metabolism in diabetic mice]. 2019 Jun 30 1
15 31562809 MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling. 2019 Sep 28 1
16 31791289 PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis. 2019 Dec 2 1
17 31889779 Protective effect of ganoderic acid against the streptozotocin induced diabetes, inflammation, hyperlipidemia and microbiota imbalance in diabetic rats. 2019 Dec 2
18 29409330 Bifidobacteria and its rice fermented products on diet induced obese mice: analysis of physical status, serum profile and gene expressions. 2018 Apr 25 1
19 29738435 CREBH Regulates Systemic Glucose and Lipid Metabolism. 2018 May 8 1
20 29772707 PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism. 2018 May 16 1
21 27925195 Palmitoleic Acid Improves Metabolic Functions in Fatty Liver by PPARα-Dependent AMPK Activation. 2017 Aug 1
22 28069388 Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes. 2017 Feb 1
23 28442498 Identification and characterization of a novel PPARα-regulated and 7α-hydroxyl bile acid-preferring cytosolic sulfotransferase mL-STL (Sult2a8). 2017 Jun 1
24 28559971 Astragalus polysaccharides attenuates TNF-α-induced insulin resistance via suppression of miR-721 and activation of PPAR-γ and PI3K/AKT in 3T3-L1 adipocytes. 2017 2
25 29020627 A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response. 2017 Oct 10 5
26 29182629 Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress. 2017 1
27 27042269 Expression profiling analysis: Uncoupling protein 2 deficiency improves hepatic glucose, lipid profiles and insulin sensitivity in high-fat diet-fed mice by modulating expression of genes in peroxisome proliferator-activated receptor signaling pathway. 2016 Mar 3
28 27071062 Bilirubin Binding to PPARα Inhibits Lipid Accumulation. 2016 1
29 27497988 Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease. 2016 Oct 1
30 27543085 Interaction of PPARα With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. 2016 Dec 2
31 25748419 Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice. 2015 Apr 15 2
32 25783893 The role of chicken ovalbumin upstream promoter transcription factor II in the regulation of hepatic fatty acid oxidation and gluconeogenesis in newborn mice. 2015 May 15 1
33 24392081 Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice. 2014 1
34 24479691 Rosiglitazone and fenofibrate exacerbate liver steatosis in a mouse model of obesity and hyperlipidemia. A transcriptomic and metabolomic study. 2014 Mar 7 2
35 24657893 Cardiomyocyte specific peroxisome proliferator-activated receptor-α overexpression leads to irreversible damage in ischemic murine heart. 2014 May 2 1
36 24865983 Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice. 2014 Jul 15 2
37 24993155 Discovery of biaryl-4-carbonitriles as antihyperglycemic agents that may act through AMPK-p38 MAPK pathway. 2014 Aug 25 1
38 23042378 Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice. 2013 Feb 2
39 23196711 Therapy with Astragalus polysaccharides rescues lipotoxic cardiomyopathy in MHC-PPARα mice. 2013 Mar 4
40 23211520 Chronic mild stress alters circadian expressions of molecular clock genes in the liver. 2013 Feb 1 1
41 23238934 Impact of L-FABP and glucose on polyunsaturated fatty acid induction of PPARα-regulated β-oxidative enzymes. 2013 Feb 1 8
42 23376064 Anti-diabetic effect of amorphastilbol through PPARα/γ dual activation in db/db mice. 2013 Mar 1 1
43 23533380 Inhibitors of Fatty Acid Synthesis Induce PPAR α -Regulated Fatty Acid β -Oxidative Genes: Synergistic Roles of L-FABP and Glucose. 2013 3
44 23747828 High glucose potentiates L-FABP mediated fibrate induction of PPARα in mouse hepatocytes. 2013 Aug 3
45 23762402 Concurrent activation of liver X receptor and peroxisome proliferator-activated receptor alpha exacerbates hepatic steatosis in high fat diet-induced obese mice. 2013 1
46 23831548 Feedback looping between ChREBP and PPARα in the regulation of lipid metabolism in brown adipose tissues. 2013 3
47 24003152 Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction. 2013 Sep 17 1
48 24937386 Interactions of PPAR α and GLUT4 in DOCA/salt-induced renal injury in mice. 2013 Dec 20 2
49 22000581 Zinc deficiency exacerbates diabetic down-regulation of Akt expression and function in the testis: essential roles of PTEN, PTP1B and TRB3. 2012 Aug 1
50 22009939 Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice. 2012 Feb 1