NAD

sirtuin 1 ; Rattus norvegicus







57 Article(s)
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1 34666848 Sirtuins and neuropeptide y downregulation in Flinders Sensitive Line rat model of depression. 2022 Apr 1
2 34861210 Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models. 2022 Jan 5 4
3 35207470 The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts. 2022 Jan 26 1
4 35250263 α-Mangostin Treats Early-Stage Adjuvant-Induced Arthritis of Rat by Regulating the CAP-SIRT1 Pathway in Macrophages. 2022 1
5 34265417 Ameliorative effect of SIRT1 in postpartum depression mediated by upregulation of the glucocorticoid receptor. 2021 Sep 14 2
6 34530866 NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. 2021 Sep 16 5
7 32087266 Resveratrol protects against ethanol-induced impairment of insulin secretion in INS-1 cells through SIRT1-UCP2 axis. 2020 Jun 5
8 32228195 Dexmedetomidine protects against lidocaine-induced neurotoxicity through SIRT1 downregulation-mediated activation of FOXO3a. 2020 Sep 2
9 32360040 Curcumin Attenuates Hemorrhagic Shock and Blood Replenish Resuscitation-induced Impairment of Pulmonary Barrier Function by Increasing SIRT1 and Reducing Malondialdehyde and TNF-α Contents and Neutrophil Infiltration in Lung in a Dose-Dependent Fashion. 2020 Jul - Aug 2
10 32848753 Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1. 2020 3
11 30625381 Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock. 2019 Mar 1 2
12 30649099 Sirtuin 1 alleviates diabetic neuropathic pain by regulating synaptic plasticity of spinal dorsal horn neurons. 2019 May 2
13 31175267 Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD+-Sirt1 signaling. 2019 Jun 7 2
14 31551807 CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD+/Sirt1 Signaling Pathway. 2019 1
15 31583043 The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics. 2019 3
16 29253500 Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway. 2018 Jan 15 2
17 31938369 Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats. 2018 2
18 28017962 SIRT1 plays a neuroprotective role in traumatic brain injury in rats via inhibiting the p38 MAPK pathway. 2017 Feb 2
19 28427145 Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis. 2017 May 16 1
20 28688179 Resveratrol attenuates excessive ethanol exposure induced insulin resistance in rats via improving NAD+ /NADH ratio. 2017 Nov 3
21 28751004 Polyphenols activate energy sensing network in insulin resistant models. 2017 Sep 25 1
22 27035562 NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity. 2016 May 6
23 27061137 SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Novel regulation by HIF-1α and NF-κB signaling. 2016 Jun 1
24 27102823 Dietary proanthocyanidins boost hepatic NAD(+) metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats. 2016 Apr 22 2
25 27357440 Exogenous Hydrogen Sulfide Postconditioning Protects Isolated Rat Hearts From Ischemia/Reperfusion Injury Through Sirt1/PGC-1α Signaling Pathway. 2016 Jul 27 2
26 27614022 The metabolic sensor Sirt1 and the hypothalamus: Interplay between peptide hormones and pro-hormone convertases. 2016 Dec 15 1
27 25411384 Theobromine increases NAD⁺/Sirt-1 activity and protects the kidney under diabetic conditions. 2015 Feb 1 2
28 25684941 Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach. 2015 Feb 14 2
29 25766524 SIRT1 suppresses doxorubicin-induced cardiotoxicity by regulating the oxidative stress and p38MAPK pathways. 2015 1
30 25798922 Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance. 2015 1
31 25849131 Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network. 2015 May 2
32 25863291 NAD(+)-dependent SIRT1 deactivation has a key role on ischemia-reperfusion-induced apoptosis. 2015 Jul 1
33 25925963 Middle-aged rats orally supplemented with gel-encapsulated catechin favorably increases blood cytosolic NADPH levels. 2015 Apr 15 2
34 25965594 SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism. 2015 Jul 15 2
35 26124049 Activation of insulin signaling and energy sensing network by AICAR, an AMPK activator in insulin resistant rat tissues. 2015 Nov 2
36 26185373 Losartan activates sirtuin 1 in rat reduced-size orthotopic liver transplantation. 2015 Jul 14 1
37 26221253 Intrathecal SRT1720, a SIRT1 agonist, exerts anti-hyperalgesic and anti-inflammatory effects on chronic constriction injury-induced neuropathic pain in rats. 2015 2
38 26544624 Enhancement of NAD⁺-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells. 2015 Dec 15 5
39 23384296 Exogenous NAD(+) supplementation protects H9c2 cardiac myoblasts against hypoxia/reoxygenation injury via Sirt1-p53 pathway. 2014 Apr 6
40 24239904 Mass spectrometric studies on the in vivo metabolism and excretion of SIRT1 activating drugs in rat urine, dried blood spots, and plasma samples for doping control purposes. 2014 Jan 1
41 24241058 Enhanced activation of NAD(P)H: quinone oxidoreductase 1 attenuates spontaneous hypertension by improvement of endothelial nitric oxide synthase coupling via tumor suppressor kinase liver kinase B1/adenosine 5'-monophosphate-activated protein kinase-mediated guanosine 5'-triphosphate cyclohydrolase 1 preservation. 2014 Feb 2
42 24296261 Sirtuin1 and autophagy protect cells from fluoride-induced cell stress. 2014 Feb 4
43 24586272 Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition. 2014 1
44 25314136 Resveratrol increases nitric oxide production in the rat thick ascending limb via Ca2+/calmodulin. 2014 2
45 25339333 [Effect and mechanism of high-dose Vitamin B3 on granulopoiesis in normal rat]. 2014 Oct 1
46 23422569 SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging. 2013 May 1 2
47 24183892 Potential neuroprotective effects of SIRT1 induced by glucose deprivation in PC12 cells. 2013 Dec 17 2
48 22113495 Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1. 2012 Mar 27 2
49 20362304 Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle. 2011 Mar 2
50 21541336 Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. 2011 Apr 26 2