| 1 |
35023537 | A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy. | 2022 Jan 31 |
1 |
| 2 |
35570516 | Synthesis, Characterisation and Docking Studies of Thioxoquinoline Derivatives as Potential Anti-Alzheimer Agents. | 2022 May 13 |
1 |
| 3 |
32660255 | Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy. | 2021 Jan 20 |
1 |
| 4 |
34391837 | Platelet-armored nanoplatform to harmonize janus-faced IFN-γ against tumor recurrence and metastasis. | 2021 Oct 10 |
2 |
| 5 |
31509830 | Rapid Estrogen and Progesterone Signaling to Dendritic Spine Formation via Cortactin/Wave1-Arp2/3 Complex. | 2020 |
1 |
| 6 |
32190166 | VGLUT2/Cdk5/p25 Signaling Pathway Contributed to Inflammatory Pain by Complete Freund's Adjuvant. | 2020 |
2 |
| 7 |
32666227 | CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPP. | 2020 Oct |
1 |
| 8 |
32692785 | Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization. | 2020 |
1 |
| 9 |
32883957 | Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy. | 2020 Sep 3 |
1 |
| 10 |
32974274 | Identification of Quinazolinone Analogs Targeting CDK5 Kinase Activity and Glioblastoma Cell Proliferation. | 2020 |
2 |
| 11 |
29944965 | CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the CDK5 and AKT signaling pathways. | 2019 Jun |
1 |
| 12 |
30911317 | Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells. | 2019 |
1 |
| 13 |
31073393 | Computational Simulations Identified Two Candidate Inhibitors of Cdk5/p25 to Abrogate Tau-associated Neurological Disorders. | 2019 |
1 |
| 14 |
31163256 | Myricetin prevents thapsigargin-induced CDK5-P66Shc signalosome mediated pancreatic β-cell dysfunction. | 2019 Sep |
1 |
| 15 |
31354714 | Cdk5 Deletion Enhances the Anti-inflammatory Potential of GC-Mediated GR Activation During Inflammation. | 2019 |
3 |
| 16 |
31395805 | Future Aspects of CDK5 in Prostate Cancer: From Pathogenesis to Therapeutic Implications. | 2019 Aug 9 |
1 |
| 17 |
29111393 | Cyclin-dependent kinase 5-mediated phosphorylation of CHIP promotes the tAIF-dependent death pathway in rotenone-treated cortical neurons. | 2018 Jan 1 |
1 |
| 18 |
29227343 | Golgi fragmentation induced by overactivated cyclin-dependent kinase 5 is associated with isoflurane-induced neurotoxicity. | 2018 Mar 7 |
1 |
| 19 |
29308980 | Modulation of TRPA1 channel activity by Cdk5 in sensory neurons. | 2018 Jan 1 |
1 |
| 20 |
29314417 | A Nestin-Cyclin-Dependent Kinase 5-Dynamin-Related Protein 1 Axis Regulates Neural Stem/Progenitor Cell Stemness via a Metabolic Shift. | 2018 Apr |
2 |
| 21 |
29467671 | TNF-α Increases Production of Reactive Oxygen Species through Cdk5 Activation in Nociceptive Neurons. | 2018 |
1 |
| 22 |
29996940 | Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth. | 2018 Jul 11 |
1 |
| 23 |
30079618 | Amino acid sequence conservation of the algesic fragment of myelin basic protein is required for its interaction with CDK5 and function in pain. | 2018 Sep |
1 |
| 24 |
28842255 | Cyclin-dependent kinase 5 controls vasculogenic mimicry formation in non-small cell lung cancer via the FAK-AKT signaling pathway. | 2017 Oct 21 |
1 |
| 25 |
30023695 | A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers? | 2017 Jul 31 |
2 |
| 26 |
26806339 | The mechanisms regulating cyclin-dependent kinase 5 in hippocampus during systemic inflammatory response: The effect on inflammatory gene expression. | 2016 Feb |
2 |
| 27 |
26966064 | Transforming growth factor-β1 induces cell cycle arrest by activating atypical cyclin-dependent kinase 5 through up-regulation of Smad3-dependent p35 expression in human MCF10A mammary epithelial cells. | 2016 Apr 8 |
1 |
| 28 |
27053712 | Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis. | 2016 Jun 1 |
1 |
| 29 |
27371933 | Binding mechanism of CDK5 with roscovitine derivatives based on molecular dynamics simulations and MM/PBSA methods. | 2016 Jul |
4 |
| 30 |
27402274 | Increase of p25 associated with cortical neuronal death induced by hypoxia. | 2016 Sep 2 |
1 |
| 31 |
25346443 | Cyclin-dependent kinase 5 regulates degranulation in human eosinophils. | 2015 Apr |
1 |
| 32 |
25829494 | Heat shock inhibition of CDK5 increases NOXA levels through miR-23a repression. | 2015 May 1 |
2 |
| 33 |
26002103 | CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death. | 2015 Aug 15 |
1 |
| 34 |
26018459 | Cyclin-dependent kinase 5 regulates the proliferation, motility and invasiveness of lung cancer cells through its effects on cytoskeletal remodeling. | 2015 Sep |
2 |
| 35 |
26160434 | CDK5 knockdown in astrocytes provide neuroprotection as a trophic source via Rac1. | 2015 Sep |
1 |
| 36 |
24498195 | ERK MAP kinase activation in spinal cord regulates phosphorylation of Cdk5 at serine 159 and contributes to peripheral inflammation induced pain/hypersensitivity. | 2014 |
2 |
| 37 |
25117211 | Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. | 2014 Dec |
1 |
| 38 |
23042366 | Osteosarcoma cells induce endothelial cell proliferation during neo-angiogenesis. | 2013 Apr |
1 |
| 39 |
24058495 | Molecular basis of differential selectivity of cyclobutyl-substituted imidazole inhibitors against CDKs: insights for rational drug design. | 2013 |
1 |
| 40 |
24091658 | EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells. | 2013 Oct 3 |
1 |
| 41 |
24098701 | Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia. | 2013 |
1 |
| 42 |
21465480 | Cdk5 mediates vimentin Ser56 phosphorylation during GTP-induced secretion by neutrophils. | 2012 Feb |
1 |
| 43 |
22276149 | Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis. | 2012 |
1 |
| 44 |
22496693 | Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1. | 2012 |
2 |
| 45 |
22696682 | Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway. | 2012 Aug |
1 |
| 46 |
22820052 | Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbens. | 2012 Oct 11 |
1 |
| 47 |
23185265 | Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts. | 2012 |
1 |
| 48 |
20977891 | Cdk5 interacts with Hif-1α in neurons: a new hypoxic signalling mechanism? | 2011 Mar 24 |
2 |
| 49 |
21144757 | Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25. | 2011 Jan 1 |
2 |
| 50 |
21209116 | Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance. | 2011 Mar |
1 |