Pub. Date : 2015 Sep
PMID : 26018459
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Inhibition of CDK5 by roscovitine and small interfering (si)RNA was used to investigate the mechanism of CDK5 in the process of A549 lung cancer cell proliferation, migration and invasion. | Roscovitine | cyclin dependent kinase 5 | Homo sapiens |
2 | The results demonstrated that functional inhibition of CDK5 using roscovitine and siRNA markedly suppressed the proliferation of A549 cells and resulted in a reduced tumor mass in vivo. | Roscovitine | cyclin dependent kinase 5 | Homo sapiens |