Title : Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells.

Pub. Date : 2021 Jul 17

PMID : 34273166






2 Functional Relationships(s)
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1 Using nicotinic acetylcholine receptor (nAChR) blockers alpha-bungarotoxin and hexamethonium bromide we found that the effects of nicotine on intracellular Ca2+ and oxidative stress were mediated by alpha7 and alpha3 nAChR. Nicotine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens
2 Using nicotinic acetylcholine receptor (nAChR) blockers alpha-bungarotoxin and hexamethonium bromide we found that the effects of nicotine on intracellular Ca2+ and oxidative stress were mediated by alpha7 and alpha3 nAChR. Nicotine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens