| 1 |
33307893 | Dietary γ-Glutamylcysteine: Its Impact on Glutathione Status and Potential Health Outcomes. | 2022 |
1 |
| 2 |
34878535 | Patient-derived gene and protein expression signatures of NGLY1 deficiency. | 2022 Feb 21 |
1 |
| 3 |
35367340 | Functional role of the SLC7A11-AS1/xCT axis in the development of gastric cancer cisplatin-resistance by a GSH-dependent mechanism. | 2022 May 1 |
1 |
| 4 |
35455093 | The Impact of Genetic Polymorphisms in Glutamate-Cysteine Ligase, a Key Enzyme of Glutathione Biosynthesis, on Ischemic Stroke Risk and Brain Infarct Size. | 2022 Apr 18 |
1 |
| 5 |
33396157 | Synthesis of glutathione as a central aspect of PAH toxicity in liver cells: A comparison between phenanthrene, Benzo[b]Fluoranthene and their mixtures. | 2021 Jan 15 |
2 |
| 6 |
33509464 | Gly-Pro-Ala peptide and FGSHF3 exert protective effects in DON-induced toxicity and intestinal damage via decreasing oxidative stress. | 2021 Jan |
1 |
| 7 |
34179023 | CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing Cells to Oxidative Stress. | 2021 |
6 |
| 8 |
34678726 | Nuclear factor kappa-B contributes to cigarette smoke tolerance in pancreatic ductal adenocarcinoma through cysteine metabolism. | 2021 Dec |
1 |
| 9 |
34829633 | Siegesbeckiae Herba Extract and Chlorogenic Acid Ameliorate the Death of HaCaT Keratinocytes Exposed to Airborne Particulate Matter by Mitigating Oxidative Stress. | 2021 Nov 4 |
1 |
| 10 |
32312817 | Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. | 2020 May 5 |
1 |
| 11 |
32715377 | Genetic variants in glutamate cysteine ligase confer protection against type 2 diabetes. | 2020 Aug |
1 |
| 12 |
32877752 | hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage. | 2020 Nov |
1 |
| 13 |
29921882 | Quercetin attenuates toosendanin-induced hepatotoxicity through inducing the Nrf2/GCL/GSH antioxidant signaling pathway. | 2019 Jan |
1 |
| 14 |
31447878 | Drosophotoxicology: Elucidating Kinetic and Dynamic Pathways of Methylmercury Toxicity in a Drosophila Model. | 2019 |
1 |
| 15 |
32010620 | Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells. | 2019 |
1 |
| 16 |
30442344 | Polymorphisms of genes related to metabolism of lead (Pb) are associated with the metal body burden and with biomarkers of oxidative stress. | 2018 Dec |
1 |
| 17 |
28705740 | Proteomics analysis of human placenta reveals glutathione metabolism dysfunction as the underlying pathogenesis for preeclampsia. | 2017 Sep |
4 |
| 18 |
28993271 | Temporal changes in glutathione biosynthesis during the lipopolysaccharide-induced inflammatory response of THP-1 macrophages. | 2017 Dec |
2 |
| 19 |
26687633 | Insulin-like growth factor 1 specifically up-regulates expression of modifier subunit of glutamate-cysteine ligase and enhances glutathione synthesis in SH-SY5Y cells. | 2016 Jan 15 |
2 |
| 20 |
26698668 | Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels. | 2016 Mar |
1 |
| 21 |
27193186 | The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer. | 2016 May 19 |
1 |
| 22 |
27284370 | Nuclear localization of glutamate-cysteine ligase is associated with proliferation in head and neck squamous cell carcinoma. | 2016 Jun |
1 |
| 23 |
27288283 | 9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction. | 2016 Aug |
3 |
| 24 |
27638861 | Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis. | 2016 Dec |
1 |
| 25 |
25353619 | Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis. | 2015 Nov 10 |
1 |
| 26 |
25620030 | Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. | 2015 Feb 9 |
2 |
| 27 |
25687825 | Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability. | 2015 Jun |
1 |
| 28 |
26229077 | Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. | 2015 Aug 18 |
1 |
| 29 |
24557597 | Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate-cysteine ligase subunits. | 2014 May |
2 |
| 30 |
24696865 | Genetic polymorphisms in glutathione (GSH-) related genes affect the plasmatic Hg/whole blood Hg partitioning and the distribution between inorganic and methylmercury levels in plasma collected from a fish-eating population. | 2014 |
2 |
| 31 |
23062287 | Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1. | 2013 Sep |
1 |
| 32 |
23129588 | Chronic depletion of glutathione exacerbates ventricular remodelling and dysfunction in the pressure-overloaded heart. | 2013 Feb 1 |
1 |
| 33 |
23724032 | The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice. | 2013 |
1 |
| 34 |
23743623 | Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma. | 2013 Sep |
1 |
| 35 |
23808636 | Glutathione (GSH) and the GSH synthesis gene Gclm modulate plasma redox and vascular responses to acute diesel exhaust inhalation in mice. | 2013 Jul |
1 |
| 36 |
23827356 | Polymorphisms in glutathione-related genes modify mercury concentrations and antioxidant status in subjects environmentally exposed to methylmercury. | 2013 Oct 1 |
1 |
| 37 |
23892356 | Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: alterations in the activities and protein expression of glutathione-related enzymes. | 2013 Dec |
1 |
| 38 |
24359630 | Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress. | 2013 Dec 23 |
2 |
| 39 |
22824862 | Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice. | 2012 Sep 15 |
1 |
| 40 |
23152058 | ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction. | 2012 Nov 15 |
4 |
| 41 |
20970495 | Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal. | 2011 Jan 1 |
1 |
| 42 |
21105962 | No association between glutathione-synthesis-related genes and Japanese schizophrenia. | 2011 Feb |
2 |
| 43 |
21657237 | Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits. | 2011 Jul 26 |
1 |
| 44 |
21967497 | Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice. | 2011 Oct |
1 |
| 45 |
20159942 | Inhibitor of kappaB kinase beta regulates redox homeostasis by controlling the constitutive levels of glutathione. | 2010 May |
2 |
| 46 |
20712757 | Assessing oxidative pathway genes as risk factors for bipolar disorder. | 2010 Aug |
1 |
| 47 |
18449862 | Association study between the genetic polymorphisms of glutathione-related enzymes and schizophrenia in a Japanese population. | 2009 Jan 5 |
1 |
| 48 |
18812186 | Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. | 2009 Feb-Apr |
1 |
| 49 |
19153097 | Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death. | 2009 May |
2 |
| 50 |
19200344 | Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. | 2009 Apr |
1 |