2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 3 ; Mus musculus







256 Article(s)
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51 27592222 Protective role of ACE2-Ang-(1-7)-Mas in myocardial fibrosis by downregulating KCa3.1 channel via ERK1/2 pathway. 2016 Nov 1
52 27656657 Exendin-4 Promotes Survival of Mouse Pancreatic β-Cell Line in Lipotoxic Conditions, through the Extracellular Signal-Related Kinase 1/2 Pathway. 2016 1
53 27720869 Caffeic acid attenuated acetaminophen-induced hepatotoxicity by inhibiting ERK1/2-mediated early growth response-1 transcriptional activation. 2016 Dec 25 1
54 28123432 Nerve growth factor protects against palmitic acid-induced injury in retinal ganglion cells. 2016 Nov 1
55 25082544 Dexmedetomidine inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated microglia by suppression of extracellular signal-regulated kinase. 2015 Mar 1
56 25482070 S100B is required for high glucose-induced pro-fibrotic gene expression and hypertrophy in mesangial cells. 2015 Feb 1
57 25670857 Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway. 2015 Mar 20 1
58 25677194 Involvement of mitogen-activated protein kinase and NF-κB signaling pathways in perfluorooctane sulfonic acid-induced inflammatory reaction in BV2 microglial cells. 2015 Dec 1
59 25724934 Activation of Toll-like receptor 3 increases mouse aortic vascular smooth muscle cell contractility through ERK1/2 pathway. 2015 Nov 1
60 25741790 Nerve growth factor-induced myoprotection in C2C12 muscle cells is mediated by α9β1 integrin via release of PGE2. 2015 Jul 1
61 26365345 Amphiregulin may be a new biomarker of classically activated macrophages. 2015 Oct 23 1
62 26389892 Gardenamide A Protects RGC-5 Cells from H₂O₂-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling Pathway. 2015 Sep 15 3
63 26710874 [Effects of chemerin on the proliferation of 3T3-L1 adipocytes]. 2015 Jul 14 1
64 24157283 Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways. 2014 Jan 3 2
65 24306628 G protein-coupled estrogen receptor-protein kinase A-ERK-CREB signaling pathway is involved in the regulation of mouse gubernaculum testis cells by diethylstilbestrol. 2014 Jul 1
66 24375569 Concomitant activation of the PI3K/Akt and ERK1/2 signalling is involved in cyclic compressive force-induced IL-6 secretion in MLO-Y4 cells. 2014 May 1
67 24872318 Relevant role of PKG in the progression of fibrosis induced by TNF-like weak inducer of apoptosis. 2014 Jul 1 1
68 24905940 Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis. 2014 Oct 3 1
69 25181481 mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein-dependent and Src-ERK1/2-dependent signaling pathways. 2014 2
70 25200553 Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells. 2014 Sep 9 1
71 25211343 Improved derivation efficiency and pluripotency of stem cells from the refractory inbred C57BL/6 mouse strain by small molecules. 2014 2
72 23154825 Lumican regulates ventilation-induced epithelial-mesenchymal transition through extracelluar signal-regulated kinase pathway. 2013 May 1
73 23379699 α2-Macroglobulin enhances vasculogenesis/angiogenesis of mouse embryonic stem cells by stimulation of nitric oxide generation and induction of fibroblast growth factor-2 expression. 2013 May 1 1
74 23421678 SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. 2013 Feb 20 1
75 23519140 Adenosine A1 receptors link to smooth muscle contraction via CYP4a, protein kinase C-α, and ERK1/2. 2013 Jul 1
76 23523568 A protective role for FGF-23 in local defence against disrupted arterial wall integrity? 2013 Jun 15 1
77 23664424 Up-regulation of matrix metalloproteinases-2 and -9 via an Erk1/2/NF-κB pathway in murine mast cells infected with Toxoplasma gondii. 2013 Aug-Oct 1
78 23691142 Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo. 2013 1
79 23744338 Chrysin promotes osteogenic differentiation via ERK/MAPK activation. 2013 Jul 1
80 23919458 Shikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells. 2013 Aug 6 3
81 23946691 Radicicol Inhibits iNOS Expression in Cytokine-Stimulated Pancreatic Beta Cells. 2013 Aug 2
82 24103125 [Role of epidermal growth factor signaling system in the pathogenesis of endometriosis under estrogen deprivation conditions]. 2013 Jun 1
83 24159377 Evidence for the involvement of NADPH oxidase in adenosine receptors-mediated control of coronary flow using A1 and A3 knockout mice. 2013 Aug 1 1
84 24187831 [Salidroside via ERK1/2 and PI3K/AKT/mTOR signal pathway induces mouse bone marrow mesenchymal stem cells differentiation into neural cells]. 2013 Aug 2
85 24211588 Serotonin acts as a novel regulator of interleukin-6 secretion in osteocytes through the activation of the 5-HT(2B) receptor and the ERK1/2 signalling pathway. 2013 Nov 29 1
86 21394501 The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models. 2012 Jan 1
87 21780113 PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms. 2012 May 1
88 22033125 Function of MAPK and downstream transcription factors in monomer-induced apoptosis. 2012 Jan 2
89 22160543 Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice. 2012 Feb 15 1
90 22207192 Effects of surgery and/or remifentanil administration on the expression of pERK1/2, c-Fos and dynorphin in the dorsal root ganglia in mice. 2012 Apr 1
91 22531136 Smads, p38 and ERK1/2 are involved in BMP9-induced osteogenic differentiation of C3H10T1/2 mesenchymal stem cells. 2012 Apr 1
92 22652804 TGF-beta 1 induced fibroblast proliferation is mediated by the FGF-2/ERK pathway. 2012 Jun 1 1
93 22762037 Activation of the ERK 1/2 and STAT3 signaling pathways is required for 661W cell survival following oxidant injury. 2012 2
94 22960610 Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model. 2012 Dec 1
95 20803555 CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts. 2011 Feb 1
96 21106540 C5a controls TLR-induced IL-10 and IL-12 production independent of phosphoinositide 3-kinase. 2011 Mar 1
97 21457229 Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide. 2011 Sep 1
98 21508279 Targeting inflammatory kinase as an adjuvant treatment for osteosarcomas. 2011 Apr 20 2
99 21549813 Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury. 2011 Jul 4 1
100 21669167 [Andrographolide inhibits extracellular signal-regulated kinase 1/2 signaling pathway in activated macrophages]. 2011 Jun 1