6 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 25326806 | Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9. | 2015 Feb | 1 |
2 | 25541062 | AZD6244 inhibits cisplatin-induced ERK1/2 activation and potentiates cisplatin-associated cytotoxicity in K-ras G12D preclinical models. | 2015 Mar 1 | 1 |
3 | 23815988 | Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation. | 2013 Jul 1 | 1 |
4 | 22068161 | Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene. | 2012 Feb 1 | 1 |
5 | 17237274 | Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma. | 2007 Jan | 2 |
6 | 17876044 | AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma. | 2007 Sep | 1 |