Chloroquine

caspase 3 ; Homo sapiens







32 Article(s)
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1 34102996 Demethylzeylasteral Exerts Antitumor Effects via Disruptive Autophagic Flux and Apoptotic Cell Death in Human Colorectal Cancer Cells and Increases Cell Chemosensitivity to 5-Fluorouracil. 2022 2
2 35106915 Acetylshikonin induces autophagy-dependent apoptosis through the key LKB1-AMPK and PI3K/Akt-regulated mTOR signalling pathways in HL-60 cells. 2022 Mar 2
3 34080659 Sensitizing TRAIL‑resistant A549 lung cancer cells and enhancing TRAIL‑induced apoptosis with the antidepressant amitriptyline. 2021 Jul 1
4 34510030 Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells. 2021 Sep 12 1
5 32132327 Role of autophagy and apoptosis in atrophic epithelium in oral submucous fibrosis. 2020 Mar 28 1
6 32146648 Inhibition of JNJ-26481585-mediated autophagy induces apoptosis via ROS activation and mitochondrial membrane potential disruption in neuroblastoma cells. 2020 May 1
7 32495214 The role of autophagy in the cytotoxicity induced by trastuzumab emtansine (T-DM1) in HER2-positive breast cancer cells. 2020 Jun 3 2
8 32626921 Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation. 2020 Aug 1
9 32766148 Chloroquine Triggers Cell Death and Inhibits PARPs in Cell Models of Aggressive Hepatoblastoma. 2020 1
10 32990233 [Aurora kinase-B silencing promotes apoptosis of osteosarcoma 143B cells by ULK1 phosphorylation-induced autophagy]. 2020 Sep 30 1
11 33024814 Inhibition of Autophagy Amplifies Baicalein-Induced Apoptosis in Human Colorectal Cancer. 2020 Dec 16 1
12 31269698 Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation. 2019 Jul 2 1
13 31839713 Chloroquine sensitizes MDA-MB-231 cells to osimertinib through autophagy-apoptosis crosstalk pathway. 2019 1
14 29316551 Chloroquine Enhances the Radiosensitivity of Bladder Cancer Cells by Inhibiting Autophagy and Activating Apoptosis. 2018 1
15 29435010 Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis. 2018 Mar 1
16 29658606 Chloroquine inhibits cell growth in human A549 lung cancer cells by blocking autophagy and inducing mitochondrial‑mediated apoptosis. 2018 Jun 1
17 30084802 Artesunate and chloroquine induce cytotoxic activity on cholangiocarcinoma cells via different cell death mechanisms. 2018 Jul 30 1
18 28197638 Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. 2017 Mar 1
19 28433067 Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis. 2017 May 2
20 29382424 [Inhibition of autophagy initiation stage enhances camptothecin-induced apoptosis in NCI-H1975 cells]. 2017 Dec 1
21 25807554 Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells. 2015 1
22 26022120 DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line. 2015 Jul 31 1
23 26067645 Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells. 2015 1
24 24333414 The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes. 2014 Jan 10 1
25 24751611 Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries. 2014 Jun 25 1
26 25308836 Inhibition of autophagy by chloroquine potentiates synergistically anti-cancer property of artemisinin by promoting ROS dependent apoptosis. 2014 Dec 1
27 23452820 Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. 2013 Mar 2 1
28 22638980 Differential effects of the autophagy inhibitors 3-methyladenine and chloroquine on spontaneous and TNF-α-induced neutrophil apoptosis. 2012 Oct 2
29 20980833 Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. 2011 Jan 1
30 18359172 Chloroquine-induced nitric oxide increase and cell death is dependent on cellular GSH depletion in A172 human glioblastoma cells. 2008 Apr 21 1
31 19088425 Cell growth inhibition, G2/M cell cycle arrest, and apoptosis induced by chloroquine in human breast cancer cell line Bcap-37. 2008 1
32 16391239 Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons. 2006 Apr 2