Title : Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Pub. Date : 2011 Jan

PMID : 20980833






1 Functional Relationships(s)
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1 Autophagy inhibitors bafilomycin and chloroquine significantly increased the cytotoxicity of compound C towards U251 cells, as confirmed by increase in lactate dehydrogenase release, DNA fragmentation and caspase-3 activation. Chloroquine caspase 3 Homo sapiens