Sorafenib

caspase 3 ; Homo sapiens







40 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35234063 Combination of ShuangDan Capsule and Sorafenib Inhibits Tumor Growth and Angiogenesis in Hepatocellular Carcinoma Via PI3K/Akt/mTORC1 Pathway. 2022 Jan-Dec 1
2 35241510 Combination Treatment of Sorafenib and Bufalin Induces Apoptosis in NCI-H292 Human Lung Cancer Cells In Vitro. 2022 Mar-Apr 1
3 35245519 Antitumor effects of rhamnazinon sorafenib-treated human hepatocellular carcinoma cell lines via modulation of VEGF signaling and PI3K/NF-κB p38/caspase-3 axes cross talk. 2022 May 15 3
4 33825398 Herbal formula of Bushen Jianpi combined with sorafenib inhibits hepatocellular carcinoma growth by promoting cell apoptosis and blocking the cell cycle. 2021 Apr 1
5 30522045 Synergistic Activity of Paclitaxel, Sorafenib, and Radiation Therapy in advanced Renal Cell Carcinoma and Breast Cancer. 2019 Feb 1
6 31387809 Decreased IL-6 induces sensitivity of hepatocellular carcinoma cells to sorafenib. 2019 Oct 1
7 31389193 Cell Membrane-Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme. 2019 Sep 1
8 29484394 Anti‑cancer effects of a novel Pan‑RAF inhibitor in a hepatocellular carcinoma cell line. 2018 Apr 1
9 30030148 Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer. 2018 Nov 1
10 30132846 Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells. 2018 Jan 1
11 30443188 The HDAC Inhibitor Quisinostat (JNJ-26481585) Supresses Hepatocellular Carcinoma alone and Synergistically in Combination with Sorafenib by G0/G1 phase arrest and Apoptosis induction. 2018 1
12 27807662 C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. 2017 Feb 1
13 28096271 In Hepatocellular Carcinoma miR-221 Modulates Sorafenib Resistance through Inhibition of Caspase-3-Mediated Apoptosis. 2017 Jul 15 2
14 28110575 Sorafenib inhibits 5-fluorouracil-resistant gastric cancer cell growth. 2017 May 1
15 28142087 Synergistic Activity of N-hydroxy-7-(2-naphthylthio) Heptanomide and Sorafenib Against Cancer Stem Cells, Anaplastic Thyroid Cancer. 2017 Mar 1
16 28178378 Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma. 2017 Apr 2
17 29072691 Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib. 2017 Oct 26 1
18 26662956 Synergistic effect of fisetin combined with sorafenib in human cervical cancer HeLa cells through activation of death receptor-5 mediated caspase-8/caspase-3 and the mitochondria-dependent apoptotic pathway. 2016 May 2
19 27544320 Identification of a novel oxidative stress induced cell death by Sorafenib and oleanolic acid in human hepatocellular carcinoma cells. 2016 Oct 15 1
20 27863838 Resveratrol enhances the efficacy of sorafenib mediated apoptosis in human breast cancer MCF7 cells through ROS, cell cycle inhibition, caspase 3 and PARP cleavage. 2016 Dec 1
21 29431086 Antitumoral Activity of Sorafenib in Hepatocellular Carcinoma: Effects on Cell Survival and Death Pathways, Cell Metabolism Reprogramming, and Nitrosative and Oxidative Stress. 2016 2
22 25683251 Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib. 2015 May 1
23 25687050 [Mechanisms of sorafenib induced NB4 cell apoptosis]. 2015 Feb 2
24 26057634 Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients. 2015 Aug 28 1
25 26233703 Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells. 2015 Dec 1
26 24520095 Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo. 2014 Mar 1 1
27 25136776 Sorafenib regulating ERK signals pathway in gastric cancer cell. 2014 Sep 1
28 25338583 [Effects of sorafenib on proliferation and apoptosis of human multiple myeloma cell RPMI 8226]. 2014 Oct 2
29 22006587 Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma. 2013 Jan 1
30 23243060 Induction of endoplasmic reticulum stress by sorafenib and activation of NF-κB by lestaurtinib as a novel resistance mechanism in Hodgkin lymphoma cell lines. 2013 Feb 1
31 23497499 Enhancing sorafenib-mediated sensitization to gemcitabine in experimental pancreatic cancer through EMAP II. 2013 Mar 6 1
32 23732299 Anti-proliferative actions of N'-desmethylsorafenib in human breast cancer cells. 2013 Aug 1 1
33 22176637 Treatment effects of the multikinase inhibitor sorafenib on hepatoblastoma cell lines and xenografts in NMRI-Foxn1 nu mice. 2012 Apr 1
34 20197401 Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. 2010 Mar 1
35 20473320 The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells. 2010 Jul 1
36 20950443 The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells. 2010 Oct 15 1
37 22993610 Sorafenib suppresses the cell cycle and induces the apoptosis of hepatocellular carcinoma cell lines in serum-free media. 2010 Sep 1
38 19366808 Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway. 2009 May 1 1
39 17909059 The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. 2007 Oct 1 1
40 16985072 Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways. 2006 Sep 1