Title : Lp-PLA2 silencing protects against ox-LDL-induced oxidative stress and cell apoptosis via Akt/mTOR signaling pathway in human THP1 macrophages.

Pub. Date : 2016 Sep 2

PMID : 27392709






1 Functional Relationships(s)
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1 Both PI3K inhibitor LY294002 and mTOR inhibitor rapamycin decreased the augmented caspase-3 expression and TC content induced by ox-LDL, respectively. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one caspase 3 Homo sapiens