Title : Raf/MEK/ERK signaling inhibition enhances the ability of dequalinium to induce apoptosis in the human leukemic cell line K562.

Pub. Date : 2012 Aug

PMID : 22875343






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, inhibition of ERK1/2 with U0126 enhanced the ability of DQA to potentiate imatinib-induced apoptosis, suggesting a role of the Raf/MEK/ERK pathway and the Bcr-Abl tyrosine kinase in the K562 cell survival. Imatinib Mesylate mitogen-activated protein kinase 3 Homo sapiens