Pub. Date : 2009 Aug
PMID : 19544110
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activated PKCalpha/ERK1/2 signaling inhibits tamoxifen-induced apoptosis in C6 cells. | Tamoxifen | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | In this study, we provided the evidence that PKCalpha-ERK1/2 signaling pathway plays a negative role in TAM-induced C6 cell apoptosis, and a combined utilization of TAM with inhibitors of PKCalpha or ERK1/2 could enhance the effectiveness of TAM on inhibiting tumor growth. | Tamoxifen | mitogen-activated protein kinase 3 | Homo sapiens |