Title : Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERĪ±-positive breast cancer.

Pub. Date : 2015 Nov

PMID : 26487496






1 Functional Relationships(s)
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Protein Name
Organism
1 Constitutive and Tam-induced phosphorylation of EGFR and ERK1/2 was blocked by the AR antagonist Enzalutamide, suggesting that AR-mediated EGFR activation was a mechanism of resistance in these cells. Tamoxifen mitogen-activated protein kinase 3 Homo sapiens