2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

AKT serine/threonine kinase 1 ; Rattus norvegicus







40 Article(s)
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1 35510038 Liraglutide Alleviates Diabetic Atherosclerosis through Regulating Calcification of Vascular Smooth Muscle Cells. 2022 1
2 33400052 Matrix Metalloproteinases Repress Hypertrophic Growth in Cardiac Myocytes. 2021 Apr 1
3 33602886 NOX4/Src regulates ANP secretion through activating ERK1/2 and Akt/GATA4 signaling in beating rat hypoxic atria. 2021 Mar 1 1
4 33738663 Ginsenoside Compound K Promotes Proliferation, Migration and Differentiation of Schwann Cells via the Activation of MEK/ERK1/2 and PI3K/AKT Pathways. 2021 Jun 1
5 30134819 Pharmacological postconditioning with Neuregulin-1 mimics the cardioprotective effects of ischaemic postconditioning via ErbB4-dependent activation of reperfusion injury salvage kinase pathway. 2018 Jul 31 1
6 27073387 Ginsenoside Rg1 protects against neurodegeneration by inducing neurite outgrowth in cultured hippocampal neurons. 2016 Feb 1
7 27085942 The study of traditional Chinese medical elongated-needle therapy promoting neurological recovery mechanism after spinal cord injury in rats. 2016 Jul 1 3
8 27538649 Xenon-delayed postconditioning attenuates spinal cord ischemia/reperfusion injury through activation AKT and ERK signaling pathways in rats. 2016 Sep 15 1
9 25338292 Repetitive ischemic preconditioning attenuates inflammatory reaction and brain damage after focal cerebral ischemia in rats: involvement of PI3K/Akt and ERK1/2 signaling pathway. 2015 Apr 2
10 25533999 bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. 2015 Mar 1
11 25999679 Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial cells. 2015 1
12 26099282 Osteopontin induces vascular endothelial growth factor expression in articular cartilage through PI3K/AKT and ERK1/2 signaling. 2015 Sep 1
13 26296503 Morphine preconditioning confers cardioprotection in doxorubicin-induced failing rat hearts via ERK/GSK-3β pathway independent of PI3K/Akt. 2015 Nov 1 1
14 26347199 A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liver. 2015 1
15 24464033 Akt and Erk1/2 activate the ornithine decarboxylase/polyamine system in cardioprotective ischemic preconditioning in rats: the role of mitochondrial permeability transition pores. 2014 May 1
16 24467537 Semen cassiae attenuates myocardial ischemia and reperfusion injury in high-fat diet streptozotocin-induced type 2 diabetic rats. 2014 1
17 24995704 Involvement of two distinct signalling pathways in IGF-1-mediated central control of hypotensive effects in normotensive and hypertensive rats. 2014 Sep 1
18 22674052 Fluoxetine upregulates phosphorylated-AKT and phosphorylated-ERK1/2 proteins in neural stem cells: evidence for a crosstalk between AKT and ERK1/2 pathways. 2013 Feb 1
19 23219579 Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats. 2013 Feb 4 1
20 23460471 Snail mediates PDGF-BB-induced invasion of rat bone marrow mesenchymal stem cells in 3D collagen and chick chorioallantoic membrane. 2013 Sep 1
21 23889671 Simvastatin induces a central hypotensive effect via Ras-mediated signalling to cause eNOS up-regulation. 2013 Oct 1
22 22147269 Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. 2012 May 1
23 22490886 Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells. 2012 May 10 1
24 22575563 Involvement of phosphatidylinositol 3-kinase/Akt on basic fibroblast growth factor-induced glial cell line-derived neurotrophic factor release from rat glioma cells. 2012 Jun 29 1
25 21699895 Carboxymethylated chitosan stimulates proliferation of Schwann cells in vitro via the activation of the ERK and Akt signaling pathways. 2011 Sep 30 1
26 22019741 Deprenyl prevents MPP(+)-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk. 2011 Dec 18 1
27 19879250 Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells. 2010 Mar 1 1
28 20404059 Phosphorylation of phosphatidylinositol-3-kinase-protein kinase B and extracellular signal-regulated kinases 1/2 mediate reoxygenation-induced cardioprotection during hypoxia. 2010 Mar 1
29 18975057 Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers. 2009 Jan 1
30 19235132 Insulin regulation of proliferation involves activation of AKT and ERK 1/2 signaling pathways in vascular smooth muscle cells. 2009 May 1
31 19318234 Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction. 2009 Jun 1
32 17267947 Endothelial cell-pericyte cocultures induce PLA2 protein expression through activation of PKCalpha and the MAPK/ERK cascade. 2007 Apr 1
33 15358610 Ischemic preconditioning protects by activating prosurvival kinases at reperfusion. 2005 Feb 1
34 15834331 Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal. 2005 Apr 15 1
35 15922325 Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2). 2005 Jun 1 1
36 15240011 Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1. 2004 Oct 1
37 12753092 The same cellular signaling pathways mediate survival in sensory neurons that switch their trophic requirements during development. 2003 Jun 3
38 12850696 ERK/MAPK-dependent PI3K/Akt phosphorylation through VEGFR-1 after VEGF stimulation in activated hepatic stellate cells. 2003 Jul 1
39 11502202 Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways. 2001 Aug 1
40 10574325 Involvement of PI 3-kinase and activated ERK in facilitating insulin-stimulated triacylglycerol synthesis in hepatocytes. 1999 Oct 1