pregna-4,17-diene-3,16-dione

nuclear receptor subfamily 1, group H, member 4 ; Mus musculus







21 Article(s)
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1 33529916 Z-guggulsterone induces PD-L1 upregulation partly mediated by FXR, Akt and Erk1/2 signaling pathways in non-small cell lung cancer. 2021 Apr 1
2 32446390 Promotion of lipogenesis by PPARγ-activated FXR expression in adipocytes. 2020 Jun 18 1
3 30638990 Probucol ameliorates hepatic stellate cell activation and autophagy is associated with farnesoid X receptor. 2019 Feb 1
4 31450152 Hepatoprotection of yangonin against hepatic fibrosis in mice via farnesoid X receptor activation. 2019 Oct 1
5 29377207 Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. 2018 Jul 1
6 29660435 Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro. 2018 Jun 1 1
7 29721568 Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor. 2018 May 23 1
8 27773935 Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation. 2017 Jan 1
9 28696246 Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. 2017 Nov 1
10 28987596 Computational discovery and experimental verification of farnesoid X receptor agonist auraptene to protect against cholestatic liver injury. 2017 Dec 15 1
11 25143196 Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice. 2015 Feb 2
12 25655198 Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis. 2015 Mar 15 1
13 26040663 Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice. 2015 Nov 1
14 24999355 Amiloride and guggulsterone suppression of esophageal cancer cell growth in vitro and in nude mouse xenografts. 2014 Feb 1
15 25278094 Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor. 2014 Nov 15 1
16 23280144 Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts. 2013 Apr 1 3
17 22492528 Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition. 2012 Jun 1
18 16675527 The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone. 2006 Sep 1
19 16778009 The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo. 2006 Oct 1
20 16140264 Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice. 2005 Oct 28 1
21 11988537 A natural product that lowers cholesterol as an antagonist ligand for FXR. 2002 May 31 2