Title : Promotion of lipogenesis by PPARγ-activated FXR expression in adipocytes.

Pub. Date : 2020 Jun 18

PMID : 32446390






1 Functional Relationships(s)
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1 Chenodeoxycholic acid (CDCA), a potent FXR agonist, enhanced the accumulation of intracellular triglycerides and the expression of the adipogenic and lipogenic genes, while guggulsterone, an FXR antagonist, suppressed CDCA-activated adipogenesis. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1, group H, member 4 Mus musculus