Title : Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice.

Pub. Date : 2015 Nov

PMID : 26040663






1 Functional Relationships(s)
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1 We further demonstrated that the changes in transporters and enzymes, as well as ameliorative liver histology in AB23A-treated mice were abrogated by FXR antagonist guggulsterone in vivo and were abrogated after FXR was silenced in vitro. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1, group H, member 4 Mus musculus