Bile Acids and Salts

nuclear receptor subfamily 1, group H, member 4 ; Mus musculus







382 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 34179517 FXR/TGR5 mediates inflammasome activation and host resistance to bacterial infection. 2021 Sep 2
52 34213907 Flavonoids from Whole-Grain Oat Alleviated High-Fat Diet-Induced Hyperlipidemia via Regulating Bile Acid Metabolism and Gut Microbiota in Mice. 2021 Jul 14 1
53 34221867 Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obesity and insulin resistance in mice. 2021 Jun 2
54 34270928 FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption. 2021 Aug 3 3
55 34281217 Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice. 2021 Jul 2 2
56 34366680 Activation of FXR Suppresses Esophageal Squamous Cell Carcinoma Through Antagonizing ERK1/2 Signaling Pathway. 2021 2
57 34479180 Tandem mass tag-based quantitative proteomic analysis of the liver reveals potential protein targets of Xiaochaihutang in CUMS model of depression. 2021 Sep 1 1
58 34585527 Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome. 2021 Dec 1
59 34596761 Cholesterol-lowering effects of taurine through the reduction of ileal FXR signaling due to the alteration of ileal bile acid composition. 2021 Oct 3
60 34604725 Ablation of liver Fxr results in an increased colonic mucus barrier in mice. 2021 Oct 4
61 34730235 Policosanol alleviates hepatic lipid accumulation by regulating bile acids metabolism in C57BL6/mice through AMPK-FXR-TGR5 cross-talk. 2021 Dec 1
62 34870866 Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron-induced hepatotoxicity. 2021 Dec 6 3
63 34970143 Ilexsaponin A1 Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice. 2021 2
64 34986301 The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE-/-FXR-/- Mice. 2021 Dec 4
65 35058750 Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System. 2021 5
66 31470114 Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice. 2020 6
67 31506275 A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice. 2020 Mar 4
68 31645370 Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition. 2020 Jan 4
69 31905247 Conditional loss of geranylgeranyl diphosphate synthase alleviates acute obstructive cholestatic liver injury by regulating hepatic bile acid metabolism. 2020 Aug 4
70 31911428 Interactions between Atorvastatin and the Farnesoid X Receptor Impair Insulinotropic Effects of Bile Acids and Modulate Diabetogenic Risk. 2020 Mar 3
71 31932631 The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids. 2020 Jan 13 1
72 31986416 Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis. 2020 Apr 1
73 32003602 Bile acid treatment and FXR agonism lower postprandial lipemia in mice. 2020 Apr 1 2
74 32018210 Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor. 2020 Mar 1
75 32034442 The glucose-lowering effects of α-glucosidase inhibitor require a bile acid signal in mice. 2020 May 2
76 32062620 Taurine attenuates hepatic steatosis in a genetic model of fatty liver disease. 2020 1
77 32116693 Naturally Occurring TPE-CA Maintains Gut Microbiota and Bile Acids Homeostasis via FXR Signaling Modulation of the Liver-Gut Axis. 2020 1
78 32190263 Optical control of the nuclear bile acid receptor FXR with a photohormone. 2020 Jan 14 2
79 32190913 Impaired Bile Secretion Promotes Hepatobiliary Injury in Sickle Cell Disease. 2020 Dec 1
80 32248018 The protective effect of obeticholic acid on lipopolysaccharide-induced disorder of maternal bile acid metabolism in pregnant mice. 2020 Jun 1
81 32258949 Farnesoid X Receptor Activation Protects Liver From Ischemia/Reperfusion Injury by Up-Regulating Small Heterodimer Partner in Kupffer Cells. 2020 Apr 2
82 32259714 Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor. 2020 Apr 5
83 32268085 Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma. 2020 Apr 7 1
84 32377219 Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis. 2020 2
85 32404932 Enhanced alcoholic liver disease in mice with intestine-specific farnesoid X receptor deficiency. 2020 Sep 1
86 32446390 Promotion of lipogenesis by PPARγ-activated FXR expression in adipocytes. 2020 Jun 18 2
87 32453814 Farnesoid X Receptor-Mediated Cytoplasmic Translocation of CRTC2 Disrupts CREB-BDNF Signaling in Hippocampal CA1 and Leads to the Development of Depression-Like Behaviors in Mice. 2020 Dec 10 2
88 32505574 3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism. 2020 Sep 3
89 32565960 Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β-catenin signaling pathway in colon cancer. 2020 Jul 2
90 32604760 Selenoneine Ameliorates Hepatocellular Injury and Hepatic Steatosis in a Mouse Model of NAFLD. 2020 Jun 26 1
91 32616182 N1-Substituted benzimidazole scaffold for farnesoid X receptor (FXR) agonists accompanying prominent selectivity against vitamin D receptor (VDR). 2020 Jul 15 5
92 32627931 Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice. 2020 Aug 3
93 32661285 Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis. 2020 Jul 13 1
94 32702472 Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells. 2020 Nov 1 1
95 32771984 Polyphenol-induced improvements in glucose metabolism are associated with bile acid signaling to intestinal farnesoid X receptor. 2020 Aug 4
96 32785220 Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet. 2020 1
97 32895154 [Bile acids regulate anorexigenic neuropeptide through p-STAT3-SOCS3 signaling in mouse hypothalamic cells]. 2020 Jul 30 3
98 32976922 Picroside II alleviates liver injury induced by alpha-naphthylisothiocyanate through AMPK-FXR pathway. 2020 Dec 1 1
99 32984886 Regulation of Lung Macrophage Activation and Oxidative Stress Following Ozone Exposure by Farnesoid X Receptor. 2020 Oct 1 2
100 33094788 Probiotics improved hyperlipidemia in mice induced by a high cholesterol diet via downregulating FXR. 2020 Nov 18 1