Bile Acids and Salts

nuclear receptor subfamily 1, group H, member 4 ; Mus musculus







382 Article(s)
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1 34686523 Molecular Regulation of Bile Acid Homeostasis. 2022 Apr 4
2 34825156 Bile acids contribute to the development of non-alcoholic steatohepatitis in mice. 2022 Jan 2
3 34825433 Effect of chronic restraint stress and western-diet feeding on colonic regulatory gene expression in mice. 2022 Apr 1
4 34856412 Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation. 2022 Feb 2
5 34862975 Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling. 2022 Jan 1
6 34881818 Lactobacillus plantarum alleviates irradiation-induced intestinal injury by activation of FXR-FGF15 signaling in intestinal epithelia. 2022 Mar 1
7 34935837 Cholesterol-lowering effect of bile salt hydrolase from a Lactobacillus johnsonii strain mediated by FXR pathway regulation. 2022 Jan 24 1
8 34973477 LKB1 in Intestinal Epithelial Cells Regulates Bile Acid Metabolism by Modulating FGF15/19 Production. 2022 2
9 35065044 Kaempferol acts on bile acid signaling and gut microbiota to attenuate the tumor burden in ApcMin/+ mice. 2022 Mar 5 2
10 35128688 Farnesoid X receptor contributes to oleanolic acid-induced cholestatic liver injury in mice. 2022 Feb 6 6
11 35147634 Dihydromyricetin prevents obesity via regulating bile acid metabolism associated with the farnesoid X receptor in ob/ob mice. 2022 Mar 7 1
12 35163821 Proglumide Reverses Nonalcoholic Steatohepatitis by Interaction with the Farnesoid X Receptor and Altering the Microbiome. 2022 Feb 8 2
13 35204252 NRF2 Activation in Autophagy Defects Suppresses a Pharmacological Transactivation of the Nuclear Receptor FXR. 2022 Feb 12 1
14 35216094 Transcriptional Control of Trpm6 by the Nuclear Receptor FXR. 2022 Feb 10 1
15 35251469 Farnesoid X Receptor Deficiency Induces Hepatic Lipid and Glucose Metabolism Disorder via Regulation of Pyruvate Dehydrogenase Kinase 4. 2022 2
16 35351576 The water extract of Radix scutellariae, its total flavonoids and baicalin inhibited CYP7A1 expression, improved bile acid, and glycolipid metabolism in T2DM mice. 2022 Jul 15 1
17 35470823 Bacillus amyloliquefaciens SC06 alleviates the obesity of ob/ob mice and improves their intestinal microbiota and bile acid metabolism. 2022 May 10 1
18 35500802 Penthorum chinense Pursh. extract attenuates non-alcholic fatty liver disease by regulating gut microbiota and bile acid metabolism in mice. 2022 Aug 10 3
19 35523117 Alisol B 23-acetate adjusts bile acid metabolisim via hepatic FXR-BSEP signaling activation to alleviate atherosclerosis. 2022 Jul 5
20 35565954 Dioscin Ameliorates Hyperuricemia-Induced Atherosclerosis by Modulating of Cholesterol Metabolism through FXR-Signaling Pathway. 2022 May 9 1
21 32198567 Deoxycholic Acid-Induced Gut Dysbiosis Disrupts Bile Acid Enterohepatic Circulation and Promotes Intestinal Inflammation. 2021 Feb 2
22 32811993 Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice. 2021 Mar 1
23 33049605 Structure-guided modification of isoxazole-type FXR agonists: Identification of a potent and orally bioavailable FXR modulator. 2021 Jan 1 2
24 33127558 Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling. 2021 1
25 33130149 DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction. 2021 Feb 1
26 33310093 Arabinoxylan combined with different glucans improve lipid metabolism disorder by regulating bile acid and gut microbiota in mice fed with high-fat diet. 2021 Jan 31 1
27 33360559 Design, synthesis, and biological studies of novel 3-benzamidobenzoic acid derivatives as farnesoid X receptor partial agonist. 2021 Feb 5 2
28 33368684 The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy. 2021 Jan 3
29 33376148 The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis. 2021 Mar 1
30 33399988 Farnesoid X receptor (FXR) agonist ameliorates systemic insulin resistance, dysregulation of lipid metabolism, and alterations of various organs in a type 2 diabetic kidney animal model. 2021 Apr 2
31 33436792 Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis. 2021 Jan 12 1
32 33568795 The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer. 2021 May 7
33 33581130 Glucagon-like peptide 1 analogue prevents cholesterol gallstone formation by modulating intestinal farnesoid X receptor activity. 2021 May 1
34 33631374 Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice. 2021 1
35 33662127 FXR-Deoxycholic Acid-TNF-α Axis Modulates Acetaminophen-Induced Hepatotoxicity. 2021 May 27 3
36 33704005 FXR activation prevents liver injury induced by Tripterygium wilfordii preparations. 2021 Jun 6
37 33783283 Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling. 2021 Dec 2
38 33811694 Neurotensin differentially regulates bile acid metabolism and intestinal FXR-bile acid transporter axis in response to nutrient abundance. 2021 May 1
39 33819483 Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. 2021 Jul 6
40 33857491 Ganoderic acid A exerted antidepressant-like action through FXR modulated NLRP3 inflammasome and synaptic activity. 2021 Jun 1
41 33890787 Four Citrus Flavanones Exert Atherosclerosis Alleviation Effects in ApoE-/- Mice via Different Metabolic and Signaling Pathways. 2021 May 5 1
42 33911126 Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists. 2021 Apr 28 1
43 33953787 Total flavonoids of Astragalus Ameliorated Bile Acid Metabolism Dysfunction in Diabetes Mellitus. 2021 1
44 33959012 Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling. 2021 5
45 33968024 Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages. 2021 1
46 33977967 Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE-/- mice. 2021 Jun 8 1
47 34045606 Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia. 2021 May 27 1
48 34124904 Apple Polyphenol Extract Improves High-Fat Diet-Induced Hepatic Steatosis by Regulating Bile Acid Synthesis and Gut Microbiota in C57BL/6 Male Mice. 2021 Jun 23 1
49 34142026 Microbiome-encoded bile acid metabolism modulates colonic transit times. 2021 Jun 25 1
50 34164827 Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling. 2021 Nov 2