4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

mechanistic target of rapamycin kinase ; Homo sapiens







33 Article(s)
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1 35280358 CMTM6 knockdown prevents glioma progression by inactivating the mTOR pathway. 2022 Feb 1
2 35341775 Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts. 2022 Jun 1 1
3 35406578 Role of mTOR through Autophagy in Esophageal Cancer Stemness. 2022 Apr 1 1
4 35489420 Endothelial miR-199a-3p regulating cell adhesion molecules by targeting mTOR signaling during inflammation. 2022 Jun 15 2
5 35604830 MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models. 2022 May 23 2
6 33440461 An aqueous extract of Prunella vulgaris L. inhibits the growth of papillary thyroid carcinoma by inducing autophagy in vivo and in vitro. 2021 Jan 13 3
7 33548371 Fumonisin B1 induces nephrotoxicity via autophagy mediated by mTORC1 instead of mTORC2 in human renal tubule epithelial cells. 2021 Mar 1
8 34265852 MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells. 2021 Sep 13 2
9 34275467 Bta-miR-34b controls milk fat biosynthesis via the Akt/mTOR signaling pathway by targeting RAI14 in bovine mammary epithelial cells. 2021 Jul 19 1
10 34367129 L-Leucine Promotes STAT1 and ISGs Expression in TGEV-Infected IPEC-J2 Cells via mTOR Activation. 2021 3
11 34718375 Epicatechin gallate prevents the de novo synthesis of fatty acid and the migration of prostate cancer cells. 2021 Dec 8 2
12 34727637 mTOR and ERK1/2 signaling participate in the process of acetate regulating lipid metabolism and HSL expression. 2021 Oct 29 2
13 34931134 Artemisinin Inhibits the Migration and Invasion in Uveal Melanoma via Inhibition of the PI3K/AKT/mTOR Signaling Pathway. 2021 1
14 34954677 Bisphenol A induces apoptosis and autophagy in murine osteocytes MLO-Y4: Involvement of ROS-mediated mTOR/ULK1 pathway. 2021 Dec 23 1
15 31698268 Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells. 2020 Jan 1
16 31985020 Adiponectin inhibits the differentiation and maturation of osteoclasts via the mTOR pathway in multiple myeloma. 2020 Apr 2
17 32014443 Melatonin attenuates vascular calcification by activating autophagy via an AMPK/mTOR/ULK1 signaling pathway. 2020 Apr 1 1
18 32047421 Resveratrol-induced brown fat-like phenotype in 3T3-L1 adipocytes partly via mTOR pathway. 2020 1
19 32112869 Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes. 2020 May 1 1
20 32215944 Oncogenic pseudogene DUXAP10 knockdown suppresses proliferation and invasion and induces apoptosis of papillary thyroid carcinoma cells by inhibition of Akt/mTOR pathway. 2020 Aug 1
21 32240637 Rab1A knockdown represses proliferation and promotes apoptosis in gastric cancer cells by inhibition of mTOR/p70S6K pathway. 2020 May 30 1
22 33356493 Valproic Acid Enhanced Apoptosis by Promoting Autophagy Via Akt/mTOR Signaling in Glioma. 2020 Jan-Dec 2
23 30798134 Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs/mTOR-dependent autophagy pathway. 2019 Apr 1
24 31030945 Targeting β3-adrenergic receptor signaling inhibits neuroblastoma cell growth via suppressing the mTOR pathway. 2019 Jun 18 1
25 31114156 Jinlong capsule inhibits migration and invasion in human glioblastoma cells via the modulation of mTOR/S6 signaling pathway. 2019 1
26 31332165 Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke. 2019 Jul 22 2
27 29575175 Cucurbitacin I induces pro-death autophagy in A549 cells via the ERK-mTOR-STAT3 signaling pathway. 2018 Jul 1
28 29726032 Fluorofenidone inhibits UV-A induced senescence in human dermal fibroblasts via the mammalian target of rapamycin-dependent SIRT1 pathway. 2018 Jul 1
29 30226616 C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation. 2018 Nov 3
30 28061443 MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling. 2017 Feb 21 5
31 28624790 Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development. 2017 Jul 18 1
32 29233105 Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway. 2017 Dec 12 1
33 27884298 MHY1485 activates mTOR and protects osteoblasts from dexamethasone. 2016 Dec 9 2