Title : C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation.

Pub. Date : 2018 Nov

PMID : 30226616






3 Functional Relationships(s)
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1 This effect was partially reversed by co-treatment with MHY1485, an activator of mammalian target of rapamycin (mTOR), demonstrating an important role for the mTOR pathway in the CerS6-mediated decrease in MCF-7 cell proliferation. 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine mechanistic target of rapamycin kinase Homo sapiens
2 This effect was partially reversed by co-treatment with MHY1485, an activator of mammalian target of rapamycin (mTOR), demonstrating an important role for the mTOR pathway in the CerS6-mediated decrease in MCF-7 cell proliferation. 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine mechanistic target of rapamycin kinase Homo sapiens
3 This effect was partially reversed by co-treatment with MHY1485, an activator of mammalian target of rapamycin (mTOR), demonstrating an important role for the mTOR pathway in the CerS6-mediated decrease in MCF-7 cell proliferation. 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine mechanistic target of rapamycin kinase Homo sapiens