AZD 6244

mechanistic target of rapamycin kinase ; Homo sapiens







4 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 26250606 Synergistic anticancer efficacy of MEK inhibition and dual PI3K/mTOR inhibition in castration-resistant prostate cancer. 2015 Nov 1
2 26498922 Simultaneous perturbation of the MAPK and the PI3K/mTOR pathways does not lead to increased radiosensitization. 2015 Oct 24 1
3 20101735 AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma. 2010 Mar 1 1
4 19637312 Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines. 2009 Nov 15 1